Article

Rhabdomyosarcomatous uterine adenosarcoma.

International Journal of Gynecological Pathology (impact factor: 1.45). 02/1985; 4(2):146-52. pp.146-52
Source: PubMed

ABSTRACT A case of rhabdomyosarcomatous adenosarcoma of the uterine cervix is described and the literature reviewed. This variant of adenosarcoma does not appear to be more malignant than other adenosarcomas. It can and should be differentiated from embryonal rhabdomyosarcoma and malignant mixed müllerian tumor because of the different prognostic implications and therapeutic approaches.

0 0
 · 
0 Bookmarks
 · 
24 Views
  • Source
    Article: Cervical Mullerian adenosarcoma with heterologous sarcomatous overgrowth: a fourth case and review of literature.
    Tito Silvio Patrelli, Salvatore Gizzo, Stefania Di Gangi, Giorgia Guidi, Mario Rondinelli, Giovanni Battista Nardelli
    [show abstract] [hide abstract]
    ABSTRACT: Uterine sarcomas are relatively rare tumors that account for approximately 1-3% of female genital tract malignancies and between 4-9% of uterine cancers. Less than 8% of all cases are Mullerian adenosarcoma, a distinctive uterine neoplasm characterized by a benign, but occasionally atypical, epithelial and a malignant, usually low-grade, stromal component, both of which should be integral and neoplastic constituents of the tumor. Mullerian adenosarcoma with sarcomatous overgrowth (MASO) is a very aggressive variant, associated with post-operative recurrence, metastases, even when diagnosed in early stage. We present a fourth MASO case derived from uterine cervix in a 72-year-old woman with metrorrhagia and a polypoid mass protruding through the cervical ostium. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, systematic pelvic lymph node dissection, omental biopsy and appendectomy were performed. Surgery treatment was associated with adjuvant whole-pelvis radiation (45 Gy) and adjuvant chemotherapy (cisplatin/ifosfamide). After nine months of follow up, the patient was free of tumor. The rarity of MASO of the cervix involves a management difficult. Most authors recommend total abdominal hysterectomy, usually accompanied by bilateral salpingo-oophorectomy. There is no common agreement on staging by lymphadenectomy during primary surgery and adjuvant chemo-radio therapy.
    BMC Cancer 06/2011; 11:236. · 3.01 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

different prognostic implications
 
embryonal rhabdomyosarcoma
 
malignant mixed müllerian tumor
 
rhabdomyosarcomatous adenosarcoma
 
therapeutic approaches
 

K T Chen