Magnetic resonance imaging of the heart.

Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710.
Magnetic resonance annual 02/1988;
Source: PubMed
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    ABSTRACT: We present a case of thrombophlebitis of the inferior vena cava (IVC) with Crohn's disease after intestinal perforation and prolonged indwelling of a catheter in the IVC. Magnetic resonance imaging demonstrated abnormal thickening and enhancement of the IVC wall. In addition, IVC thrombus formation was shown. The abnormal enhancement extended from the wall in the pericaval tissue and into the retroperitoneum, and regressed as the Crohn's disease subsided.
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    ABSTRACT: Experimental animal studies have demonstrated that changes occur in T1 and T2 relaxation, proton density and flow signal as a result of myocardial infarction and reperfusion [1, 2]. These parameters are mainly responsible for the changes in signal intensity on the magnetic resonance (MR) images. The change in signal intensity produced by myocardial ischemia is less than with infarction, and an MR contrast agent is usually required to enhance image contrast between ischemic and normal myocardium [3]. The ability of MR imaging to separate the various acute coronary syndromes has been addressed [4, 5], but requires further experimentation [4]. The purpose of this chapter is to examine the experimental data that is presently available regarding myocardial ischemia, infarction and reperfusion, and to indicate how these studies can be helpful in enhancing the potential of MR imaging for the characterization of coronary artery disease in the human subject. Already, it has been clearly demonstrated that recent myocardial infarction can be distinguished in humans and some estimation of the size of the infarction can be made [6–8]. The ability to differentiate viable from nonviable myocardium, and the place of MR contrast agents in helping to distinguish these conditions will require further animal experimentation. These studies will be useful in determining the place of MR imaging in the assessment of patients following acute myocardial ischemic events.
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