Danger of lumbar puncture in spinal cord compression.
ABSTRACT Rapid deterioration in the symptoms and signs of spinal cord compression following lumbar puncture is an unusual complication which must be thought of before undertaking this procedure as part of myelography.
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ABSTRACT: Of 478 patients treated at a single institution for prostate cancer, 29 developed spinal cord or cauda equina compression. In 5 patients, spinal cord compression was the first evidence of malignancy. Clinical features were predominantly pain, weakness, sensory and sphincter disturbance. The median duration of symptoms was 2 weeks, although the diagnosis was made rapidly at presentation. Clinical diagnosis correlated well with myelographic findings. Only 1 patient suffered neurological deterioration as a consequence of myelography. The functional outcome was dependent on the ability to walk prior to treatment. The median survival in those who were bedridden following treatment was 6 weeks (range 3.5-13) and 21 weeks (range 7-110+) in those who were ambulant following therapy.British Journal of Urology 06/1992; 69(5):530-3. DOI:10.1111/j.1464-410X.1992.tb15603.x