Effects of feeding Lactobacillus GG on lethal irradiation in mice

Tufts University, Бостон, Georgia, United States
Diagnostic Microbiology and Infectious Disease (Impact Factor: 2.46). 06/1987; 7(1):1-7. DOI: 10.1016/0732-8893(87)90063-0
Source: PubMed


Mice exposed to 1400 rads of total body irradiation experienced 80%-100% mortality in 2 wk. Bacteremia was demonstrated in all dead animals. Feeding Lactobacillus GG strain reduced Pseudomonas bacteremia and prolonged survival time in animals colonized with this organism. In animals not colonized with Pseudomonas, feeding Lactobacillus GG also produced some reduction in early deaths, and there was less Gram-negative bacteremia in these animals compared with controls.

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