Stability of individual carotenoids, retinol, and tocopherol in stored plasma

Clinical Chemistry (Impact Factor: 7.91). 10/1988; 34(9):1947.
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    ABSTRACT: We have quantitatively analyzed human plasma for the following carotenoids: all-trans-lutein, all-trans-zeaxanthin, a-cryptoxanthin, ß-cryptoxan- thin, the sum of all-trans-lycopene and its cis isomers, (/-carotene and |i-carotene. In addition, we have tenta tively identified and quantified 13-as-lute ¡n and 13- ci's-zeaxanthin in human plasma. The latter two cis isomers are also apparent in samples of two common food items, spinach and corn meal. We have analyzed the ratios of all of the members of the ß,ß family of carotenoids (zeaxanthin, ß-cryptoxanthin and li-caro tene) to their corresponding ß,E structural isomers (lutein, a-cryptoxanthin and a-carotene) in human plasma. There are marked differences in these ratios, with ß-carotene and ß-cryptoxanthin predominating in the carotene and monohydroxy-xanthophyll classes and lutein predominating in the dihydroxy-xanthophyll class. These differences could be attributable to di etary intake or to specific mechanisms in the way humans absorb and utilize these compounds. J. Nutr. 120:1654-1662, 1990. INDEXINGKEYWORDS:
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