Rate of forgetting in dementia and depression.
ABSTRACT Patients with mild dementia of the Alzheimer's type (DAT), patients with major depression, and normal control subjects were examined for rate of forgetting line drawings of common objects after the groups had been equated for acquisition by the variation of stimulus exposure time. Depressed and DAT patients demonstrated learning impairments, but only the DAT group showed rapid forgetting in the first 10 min after learning to criterion. This finding suggests that some form of deficient consolidation contributes to memory loss in DAT but not in depression and implicates the disruption of different psychobiological mechanisms in these disorders. The rate of forgetting paradigm may be clinically useful for distinguishing patients with early DAT from elderly depressed patients with memory deficits. (53 ref) (PsycINFO Database Record (c) 2012 APA, all rights reserved)
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ABSTRACT: In this study we explored the rate of forgetting from long-term memory in Alzheimer's (AD) and multi-infarct (MID) dementia. For this purpose, we administered to 15 AD, 15 MID, and 22 control subjects two tasks exploring, respectively, long-term verbal and long-term visuo-spatial memory. The absolute rate of forgetting in both tasks was computed as the difference between immediate and delayed recall of memorandum. Since level of immediate recall was significantly different between groups, a proportional rate of forgetting (percentage of memorandum lost passing from immediate to delayed recall) was computed for each patient. In the verbal task (Rey's 15 words) AD patients displayed significantly larger absolute and proportional rates of forgetting than MID and control subjects. In the spatial task (Corsi block supraspan), the absolute rate of forgetting was only marginally different between groups. Nevertheless, AD patients demonstrated a larger proportional rate of forgetting than MID and normal subjects. These results point out an exalted decay of information from long-term memory store in AD patients. In the light of previous data (Corkin et al., 1984; Kopelman, 1985) we propose that long-term memory deficits in AD is due, at least in part, to an abnormal forgetting of information within the first few minutes following acquisition. Information still present in the subsequent period (10 min to several days) is retained normally. The normal rate of forgetting in MID patients, further, suggests different mechanisms underlying memory disorders in vascular and degenerative dementias.International Journal of Neuroscience 12/1993; 73(1-2):1-11. DOI:10.3109/00207459308987206 · 1.53 Impact Factor
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ABSTRACT: In 1979, Wells tabled a list of ‘major clinical features’ which he found most useful in distinguishing dementia due to organic disease from dementia occuring in the context of psychiatric conditions like depression. This article reviews recent findings on the most commonly accepted items of this list and, for several of them, concludes that the evidence is controversial. Newer aspects are then briefly considered which, when validated in longitudinal studies, may add to the clinician's range of implements during diagnostic workup.International Journal of Geriatric Psychiatry 09/1992; 7(9):629 - 638. DOI:10.1002/gps.930070904 · 3.09 Impact Factor
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ABSTRACT: This report contains the proceedings of the 1989 AMEDD Clinical Psychology Short Course. Contents: Army Clinical Psychology into the 1990s; The Administratively Separate Psychology Service: Current Status and Update; Administratively Separate Psychology Service: Current Status and Evaluation; Licensing and Credentialing Within HSC; Army Clinical Psychologists: Factors Affecting Decision to Remain in Service; Neuropsychological Assessment of HIV+ and AIDS Patients; The Effect of Emotional State on Neuropsychological Test Performance; Stress Variables and Patterns of Alcohol Consumption; The Use of Assessment Instruments in Marital Counseling; Update on Multiple Personality Disorder; Family Therapy and Anxiety Disorders: A Clinical Investigation; American Board of Professional Psychology (ABPP) Examination; Military Forensic Psychology; Forensic Psychology: Role of the Military Psychologist; The Psychologist's Role in Security Evaluations; Suicide Prevention in the U.S. Army: A Program Comes of Age; Dual Relationships: Legal and Ethical Dangers for Psychotherapists; Understanding Family and Community Violence; Peacetime Stress Casualties: Characteristics and Implications for Army Psychology; CMHA Quality Assurance Study of Stress Management Group; The Army Health Psychology Fellowship; Course After-Action Report - 1989 AMEDD Clinical Psychology Short Course.