Article

Rate of forgetting in dementia and depression.

Journal of Consulting and Clinical Psychology (Impact Factor: 4.85). 03/1987; 55(1):101-5. DOI: 10.1037/0022-006X.55.1.101
Source: PubMed

ABSTRACT Patients with mild dementia of the Alzheimer's type (DAT), patients with major depression, and normal control subjects were examined for rate of forgetting line drawings of common objects after the groups had been equated for acquisition by the variation of stimulus exposure time. Depressed and DAT patients demonstrated learning impairments, but only the DAT group showed rapid forgetting in the first 10 min after learning to criterion. This finding suggests that some form of deficient consolidation contributes to memory loss in DAT but not in depression and implicates the disruption of different psychobiological mechanisms in these disorders. The rate of forgetting paradigm may be clinically useful for distinguishing patients with early DAT from elderly depressed patients with memory deficits. (53 ref) (PsycINFO Database Record (c) 2012 APA, all rights reserved)

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