Synchronous neuroblastoma and von Recklinghausen's disease: a review of the literature.

Journal of Clinical Oncology (Impact Factor: 17.88). 02/1985; 3(1):117-20.
Source: PubMed

ABSTRACT We report an unusual case of progressive disseminated neuroblastoma occurring in a child with a family history and stigmata of von Recklinghausen's disease. A review of the literature confirms the extreme rarity of finding these two neurocristopathies in a single individual and thus undermines the widely held notion of an association--genetic or otherwise--between these two entities. We propose that synchronous neuroblastoma and von Recklinghausen's disease is accounted for by chance alone and therefore represents a randomly occurring phenomenon.

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