The relationship of psychosocial factors to prognostic indicators

University of California, Berkeley, Berkeley, California, United States
Journal of Psychosomatic Research (Impact Factor: 2.74). 02/1985; 29(2):139-53. DOI: 10.1016/0022-3999(85)90035-2
Source: PubMed


This study investigated the relationship between prognosis (estimated by histopathologic indicators) in cutaneous malignant melanoma and a comprehensive set of physical risk, demographic, psychosocial, and situational variables. These variables were derived from the medical examination, the pathology report, psychosocial self-report measures, and an hour-long videotaped interview with 59 patients from two melanoma clinics in San Francisco. Variables significantly correlated with tumor thickness were: darker skin/hair/eye coloring, longer patient delay in seeking medical attention, two correlated dimensions within an operationally defined 'Type C' constellation of characteristics, two character style measures, and less previous knowledge of melanoma and understanding of its treatment. Of these variables, delay was the most significant in a hierarchical multiple regression analysis in which tumor thickness was the dependent variable. Associations between tumor thickness and psychosocial measures of Type C were considerably stronger and more significant for subjects less than age 55, suggesting that the role of behavioral and psychosocial factors in the course of malignant melanoma is more potent for younger than for older subjects.

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    • "The possibility that personality may be a risk factor for the development of malignant tumors has been suggested [2,7,8]. Eysenck et al. [2] mentioned that personality, rather than smoking, may be strongly associated with the development of lung cancer. "
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    ABSTRACT: Background There have been scarce large-scale studies investigating the personality of patients with malignant tumors. The purpose of this study is to determine the characteristic personality in malignant tumors outpatients. Methods Three thousand and three among 5013 consecutive outpatients who consented to answer the Japanese Maudsley Personality Inventory questionnaires were divided into two groups. 603 outpatients diagnosed with malignant tumors (M group) and the other 2400 outpatients (non-M group) were enrolled in this study. We determined three scores such as introversion/extroversion (E-score), neuroticism (N-score), and lie detection (L-score). All data were used to compare the two groups. Results Average E-score was slightly higher, and average N-score was slightly lower in M group than that in non-M group, and no significant differences between the two groups. However, the average L-score in M group was significant higher than that in non-M group (p < 0.01). Conclusion Outpatients with malignant tumors showed a significantly higher L-score on MPI when compared with patients with non-malignant tumors. These results stress the importance of taking the mentality of patients with cancer into consideration when conducting treatment and care.
    World Journal of Surgical Oncology 09/2012; 10(1):187. DOI:10.1186/1477-7819-10-187 · 1.41 Impact Factor
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    • "Specifically, studies involving patients with malignant melanomas indicate that personality type predicts neither recurrence nor survival time (Canada et al., 2005). However, a greater progression of the disease was found in patients who claimed to have accepted their illness or who expressed feelings of impotence/desperation (Temoshok et al., 1985) and a positive relationship was observed between the manifestation of active coping strategies and a higher survival rate (Fawzy et al., 1993). "
    Advances in Malignant Melanoma - Clinical and Research Perspectives, 09/2011; , ISBN: 978-953-307-575-4
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    • "Other studies have mainly focused on the possible association between psychological factors, including component factors of type C personality (Temoshok et al, 1985), such as emotional suppression, helplessness/hopelessness, and cancer survival. In a recent large prospective cohort study, 578 cases of early-stage breast cancer were followed up for at least 5 years with 133 deaths from all causes; emotional suppression and helplessness/hopelessness did not increase the risk of death (Watson et al, 1999). "
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    ABSTRACT: We tested the hypothesis that personality plays a role in cancer outcome in a population-based prospective cohort study in Japan. In July 1990, 41 442 residents of Japan completed a short form of the Eysenck Personality Questionnaire-Revised and a questionnaire on various health habits, and between January 1993 and December 1997, 890 incident cases of cancer were identified among them. These 890 cases were followed up until March 2001, and a total of 356 deaths from all causes was identified among them. Cox proportional-hazards regression was used to estimate the hazard ratio (HR) of death according to four score levels on each of four personality subscales (extraversion, neuroticism, psychoticism, and lie), with adjustment for potential confounding factors. Multivariable HRs of deaths from all causes for individuals in the highest score level on each personality subscale compared with those at the lowest level were 1.0 for extraversion (95% CI=0.8–1.4; Trend P=0.73), 1.1 for neuroticism (0.8–1.6; Trend P=0.24), 1.2 for psychoticism (0.9–1.6; Trend P=0.29), and 1.0 for lie (0.7–1.5; Trend P=0.90). The data obtained in this population-based prospective cohort study in Japan do not support the hypothesis that personality is associated with cancer survival.Keywords: death from all causes, Eysenck personality questionnaire-revised, Japanese, prospective cohort study, survival
    British Journal of Cancer 05/2005; 92(11):2089-2094. DOI:10.1038/sj.bjc.6602610 · 4.84 Impact Factor
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