Aspiration pneumonia. Clinical outcome following documented aspiration.

Archives of Surgery (Impact Factor: 4.3). 02/1973; 106(1):49-52.
Source: PubMed
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    ABSTRACT: Aspiration pneumonia is common and often serious lung disease. Prognosis could be improved by effective prevention, early diagnosis and appropriate drug regimens. Since anti-microbial therapy is the key stone of treatment, it has been an area of debate and controversy. We evaluate the efficacy and safety of intravenous ofloxacin plus piperacillin. Our bacteriologic results show frequent pluri micro-organism cultures in sputum and frequent isolation of staphylococci in culture specimens. Clinical and bacteriological results demonstrate that intravenous ofloxacin plus piperacillin is effective (success = 28/30) and safe (no side effects) for the treatment of aspiration pneumonia.
    Médecine et Maladies Infectieuses 05/1993; 23:409-412. DOI:10.1016/S0399-077X(05)80965-5 · 0.91 Impact Factor
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    ABSTRACT: Dysphagia, which can result in aspiration pneumonia and death, is a well-known problem in patients with dementia and Parkinson's disease. There are few studies on dysphagia in patients with dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD), especially studies objectively documenting the type of swallowing dysfunction. The aim of this study was therefore to investigate the prevalence, and define the actual swallowing dysfunction according to a videofluoroscopic swallowing examination (VFSE) in patients with DLB and PDD. Eighty-two consecutive patients with DLB or PDD in a clinical follow-up program were asked about symptoms of dysphagia. Those experiencing dysphagia were examined with VFSE. Prevalence and type of swallowing dysfunction was recorded. Twenty-six patients (32%) reported symptoms of dysphagia such as swallowing difficulties or coughing. Twenty-four (92%) of these had a documented swallowing dysfunction on VFSE. Eighty-eight percent suffered from pharyngeal dysfunction. Almost all DLB or PDD patients with subjective signs of dysphagia had pathologic results on VFSE, the majority of pharyngeal type. This type of dysphagia has not been reported in DLB before. The results have clinical implications and highlight the importance of asking for and examining swallowing function to prevent complications such as aspiration.
    BMC Neurology 10/2013; 13(1):140. DOI:10.1186/1471-2377-13-140 · 2.49 Impact Factor
  • Journal of Surgical Research 05/1974; 16(4):324-9. DOI:10.1016/0022-4804(74)90050-X · 2.12 Impact Factor