Double-blind and open studies of lithium prophylaxis in affective disorders

Psychiatria, neurologia, neurochirurgia 01/1973; 76(6):501-10.
Source: PubMed


There is now abundant evidence that the morbidity of recurrent affective disorders continues to be high even when treated by the best conventional methods. Continuous lithium treatment has now been shown to considerably reduce the morbidity of both unipolar recurrent depressive patients and both the manic and depressive phase of the bipolar patients.

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