Cytogenetic survey of XYY males in two juvenile court populations, with a case report.

Journal of Medical Genetics (Impact Factor: 5.64). 10/1972; 9(3):287-8. DOI: 10.1136/jmg.9.3.287
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    ABSTRACT: Two populations of phenotypic males, twelve 47,XYY and twelve 47,XXY patients, when compared for behavior disability, sexual practices, and social interaction, revealed that the XYY males had behavior disability involving a predominance of impulsive acting out and poor long term planning. By contrast, the XXY males manifested a deficiency or inhibition of action. With regard to sexual practices, the XYY males reported a greater frequency and diversity of sexual experience and imagery than did the XXY males, who appear to be sexually inert by comparison. For both XYY and XXY men, being alone took preference over group participation. The XXY men were more characterized by inertia and reclusiveness, while the XYY men were mobile and more likely to intrude on other people and their property.
    Clinical Genetics 02/1974; 6(5):370-82. · 3.65 Impact Factor
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    ABSTRACT: This paper reports the testicular size and shape of 12 men with 47,XYY, 14 men with 47,XXY, and 52 matched controls with 46,XY. The abnormal karyotypes were identified in a systematic population search for XYY and XXY men. The subjects and their matched controls were examined in a double-blind fashion. The testes of the XYY men showed no significant differences from those of their XY controls for volume or shape. This indicates that previous reports of abnormal testes in XYYs reflect selection and publication bias and do not provide an accurate description of the condition of 47,XYY men's testicles. As expected, the testes of the XXY men were significantly smaller than those of their XY controls, and there was also a difference in shape. However, the mean size in this sample of XXYs was larger than in previous reports on Klinefelter syndrome patients, indicating that previous reports on XXYs, identified in clinics for male hypogonadism and other institutions, also suffered from selection bias.
    The American Journal of Human Genetics 12/1979; 31(6):697-703. · 10.99 Impact Factor
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    ABSTRACT: Consecutive X and Y chromatin survey among 1,581 Japanese juvenile delinquents had been undertaken for three years. Among 1,371 males, five 47,XYY males and four 47,XXY males were found (0.36% and 0.29% respectively), while no numerical abnormalities of X chromatin were found in 210 females. Frequency of 47,XYY males in the present study is significantly higher than that of newborns. With respect to sample size, for which the frequencies of 47,XYY and 47,XXY males have been estimated, a possible bias in the studies reported previously was suggested.
    The Japanese Journal of Human Genetics 04/1979; 24(1):21-5.

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