Conditioned reflex salivary secretion in man.

Department of Physiology (Oral Biology), The Medical School, University Walk, Bristol BS8 1TH UK
Archives of Oral Biology (Impact Factor: 1.55). 09/1970; 15(8):761-7. DOI: 10.1016/0003-9969(70)90039-7
Source: PubMed

ABSTRACT Human subjects have been conditioned to secrete saliva in response to sounding a buzzer and switching on a light. Orange juice injected onto the dorsum of the tongue was used as the unconditioned stimulus during the conditioning sequences. Negative results obtained in the early experiments of the present series, and by other workers, have been attributed to failure to obtain a discrete secretory response with each conditioning stimulus. Pre-formed conditioned reflexes were also demonstrated in response to the sight or suggestion of food although these responses were small and not consistent.RésuméDes sujets ont été conditionnés pour sécréter de la salive en allumant une lumière et en entendant une sonnerie. Du jus d'orange, placé sur le dos de la langue, sert de stimulus inconditionné pendant les phases du conditionnement. Les résultats négatifs, observés au cours de recherches antérieures par les auteurs et d'autres chercheurs, ont été mis en rapport avec l'incapacité d'obtenir une réponse sécrétoire discrète avec chaque stimulus conditionné. Des réflexes conditionnés préformés sont aussi mis en évidence à la vue ou par l'évocation de nourriture bien que ces réponses soient faibles et non constantes.ZusammenfassungVersuchspersonen wurden dazu angeleitet, Speichel als Reaktion auf des Geräusch eines Summers und das Einschalten von Licht zu sezernieren. Auf den Zungenrücken gespritzter Orangensaft wurde als nichtbedingter Reiz während der konditionierenden Übungen benützt. Negative Ergebnisse bei den ersten Versuchen dieser Reihe und von anderen Autoren waren darauf zurückzuführen, daβ es nicht gelang, eine diskrete sekretorische Reaktion bei jedem bedingten Reiz zu erhalten. Vorgeformte bedingte Reflexe wurden auch als Reaktion auf das Sehen oder das Sich-vorstellen von Nahrung nachgewiesen, obwohl diese Reaktionen gering und nicht einheitlich waren.

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