Article

Hemodynamic effects of antihypertensive drugs.

American family physician (impact factor: 1.7). 07/1983; 27(6):137-42. pp.137-42
Source: PubMed

ABSTRACT Elevated total peripheral resistance and normal cardiac output are the hemodynamic characteristics of chronic essential hypertension. One approach to treating hypertension matches the individual pathophysiology with the hemodynamic effects of antihypertensive drugs. Antiadrenergic drugs are appropriate second-step therapy in many cases of established hypertension; by reducing total peripheral resistance, these agents can reduce blood pressure while sparing cardiac output and renal blood flow. The physician should treat elderly hypertensive patients cautiously and consider using drug with a favorable hemodynamic profile.

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Keywords

Antiadrenergic drugs
 
antihypertensive drugs
 
blood pressure
 
chronic essential hypertension
 
Elevated total peripheral resistance
 
favorable hemodynamic profile
 
hemodynamic characteristics
 
hypertension
 
hypertension matches
 
individual pathophysiology
 
normal cardiac output
 
renal blood flow
 
sparing cardiac output
 
total peripheral resistance
 

H D Itskovitz