Article

Hepatic aryl hydrocarbon hydroxylase activities in coho salmon (Oncorhynchus kisutch) exposed to petroleum hydrocarbons.

Comparative Biochemistry and Physiology Part C Comparative Pharmacology and Toxicology 02/1984; 79(2):337-41. pp.337-41
Source: PubMed

ABSTRACT Coho salmon exposed to the water soluble fraction (WSF) of Cook Inlet crude oil for a maximum of 30 days showed a greater than three-fold increase in hepatic aryl hydrocarbon hydroxylase activity. The initial increase in enzyme activity appeared between 2 and 5 days of exposure and increased as a function of increased exposure time. Persistence of the induced enzyme activity was dependent on the length and the concentration of WSF exposure. Handling stress had no effect on the AHH activity, but starvation caused a decrease in the activity.

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Keywords

Coho salmon
 
Cook Inlet crude oil
 
decrease
 
enzyme activity
 
exposure time
 
Handling stress
 
hepatic aryl hydrocarbon hydroxylase activity
 
induced enzyme activity
 
three-fold increase
 
water soluble fraction
 
WSF
 
WSF exposure