Parents of patient with obsessive-compulsive disorder

Psychological Medicine (Impact Factor: 5.43). 12/1983; 13(4):807-11. DOI: 10.1017/S0033291700051515
Source: PubMed

ABSTRACT Family histories obtained from 27 patients with obsessive-compulsive disorder failed to find a single parent with the disorder. To augment the family history data the Leyton Obsessional Inventory was completed by a subset of 10 patients and by their 20 parents. Although as a group parents showed lower Leyton Obsessional Inventory symptom scores than their obsessional offspring, 3 parents who had not been identified by family history were distinguished by high symptom scores in the absence of significant resistance or interference.

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    • "Note: CBFT = cognitive-behavioral family-based therapy; CDI = Children's Depression Inventory (Kovacs, 1992); MASC = Multidimensional Anxiety Scale for Children (March, 1997); NIMH GOCS = National Institute of Mental Health Global Obsessive-Compulsive Scale (Insel et al., 1983); Improvement = NIMH GOCS improvement ratings (i.e., not available at pretreatment; Insel et al., 1983); NA = not applicable. Main effect for time is denoted by asterisks beside the measure name. "
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    ABSTRACT: To evaluate the relative efficacy of (1) individual cognitive-behavioral family-based therapy (CBFT); (2) group CBFT; and (3) a waitlist control group in the treatment of childhood obsessive-compulsive disorder (OCD). This study, conducted at a university clinic in Brisbane, Australia, involved 77 children and adolescents with OCD who were randomized to individual CBFT, group CBFT, or a 4- to 6-week waitlist control condition. Children were assessed before and after treatment and at 3 months and 6 months following the completion of treatment using diagnostic interviews, symptom severity interviews, and self-report measures. Parental distress, family functioning, sibling distress, and levels of accommodation to OCD demands were also assessed. Active treatment involved a manualized 14-week cognitive-behavioral protocol, with parental and sibling components. By an evaluable patient analysis, statistically and clinically significant pretreatment-to-posttreatment change occurred in OCD diagnostic status and severity across both individual and group CBFT, with no significant differences in improvement ratings between these conditions. There were no significant changes across measures for the waitlist condition. Treatment gains were maintained up to 6 months of follow-up. Contrary to previous findings and expectations, group CBFT is as effective in reducing OCD symptoms for children and adolescents as individual treatment. Findings support the efficacy and durability of CBFT in treating childhood OCD.
    Journal of the American Academy of Child & Adolescent Psychiatry 02/2004; 43(1):46-62. DOI:10.1097/00004583-200401000-00014 · 6.35 Impact Factor
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    ABSTRACT: The nature of the relationship between obsessive-compulsive personality and obsessive-compulsive disorder has been the subject of considerable debate. The present article dealt with clinical opinion and reviewed empirical data bearing on this issue. It was concluded that, although the two clinical entities bear a surface similarity in terms of shared behavioral features and defenses, obsessive-compulsive personality is neither a necessary nor sufficient factor in the development of obsessive-compulsive disorder, though the latter appears to be more frequently associated with premorbid obsessive-compulsive personality patterns than with other personality patterns. Suggestions for future research study are made.
    The Journal of Psychology Interdisciplinary and Applied 04/1987; 121(2):137-48. DOI:10.1080/00223980.1987.9712651 · 0.86 Impact Factor
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    ABSTRACT: The first-degree relatives of 50 obsessive-compulsive patients and those of matched controls completed the General Health Questionnaire (GHQ) and the Leyton Obsessional Inventory (LOI). Relatives who were identified as possible 'cases' by their high GHQ scores, or by their own or informant relatives' reports, were interviewed using the Schedule for Affective Disorders and Schizophrenia. Index relatives had a significantly higher lifetime prevalence of mental illness (36%) than had those of controls (17%), due mainly to an excess of depressive and neurotic disorders. However, only one relative from each group was diagnosed as having definite obsessive-compulsive neurosis. In addition, the LOI scores were similar for the index and control relatives.
    The British Journal of Psychiatry 11/1987; 151(4):528-34. DOI:10.1192/bjp.151.4.528 · 7.34 Impact Factor
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Dennis L Murphy