Article

Schizoaffective psychoses: Genetical clues to classification

Department of Psychiatric Demography, Aarhus University Psychiatric Hospital, Denmark.
American Journal of Medical Genetics (Impact Factor: 3.23). 02/1995; 60(1):7-11. DOI: 10.1002/ajmg.1320600103
Source: PubMed

ABSTRACT The diagnostic classification of schizoaffective psychoses has varied much since Kasanin introduced the concept in 1933. The various classifications have agreed that schizoaffective psychoses present a combination of schizophreniform and affective symptoms, but the diagnostic criteria differ as to the number, quality, and time sequence of the symptoms even in recent classifications like RDC, DSM-III-R, and ICD-10. The classifications are syndromatical, and the etiology of the schizoaffective psychoses is still undetermined apart from evidence for a strong genetic factor. Results from family, twin, and adoption studies are divergent, but all the same, support a separate classification of broadly defined schizoaffective psychoses as possibly being phenotypical variations or expressions of genetic interforms between schizophrenia and affective psychoses.

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