Dietary carotenoids protect human cells from damage

Humboldt-Universität zu Berlin, Berlín, Berlin, Germany
Journal of Photochemistry and Photobiology B Biology (Impact Factor: 2.96). 01/1995; 26(3):283-5. DOI: 10.1016/1011-1344(94)07049-0
Source: PubMed


A physical chemistry technique based on singlet oxygen luminescence at about 1270 nm and a biological cell membrane technique were used to study the quenching of singlet oxygen by four carotenoids bound to the surface of lymphoid cells. All the carotenoids studied showed a beneficial effect in cell protection, but there were subtle differences between them.

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    ABSTRACT: HPLC methods (LC-MS/APCI and chiral HPLC) were used for the identification of astaxanthin derivatives from the red snow alga Chlamydomonas nivalis collected in Austrian Alps, Slovak High Tatra Mountains and Bulgarian Pirin. We observed a striking difference in the composition of astaxanthin optical isomers in C. nivalis collected in geographically distinct regions. Furthermore, algae from the Pirin Mountains differed in the dominance of astaxanthin diglucoside diesters, suggesting an alternative strategy to enhance cell viability at low temperatures.
    Phytochemistry 02/2013; 88. DOI:10.1016/j.phytochem.2013.01.003 · 2.55 Impact Factor
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    • "The esterification of astaxanthin is considered to be a mechanism allowing efficient pigment concentration in cytoplasm (Bidigare et al., 1993). The protective role of astaxanthin in snow algal cells is apparently complex, because this secondary carotenoid is also an effective antioxidant (Tinkler et al., 1994). The water content in cells is reduced when astaxanthin concentration is high, reducing the likelihood of ice crystal formation (Hoham, 1992). "
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