Article

Relationships between thyroid indices and symptoms of anxiety in depressed outpatients.

Psychiatry Service, Albuquerque Veterans Affairs Medical Center, New Mexico.
Annals of Clinical Psychiatry (impact factor: 1.49). 07/1993; 5(2):111-6. pp.111-6
Source: PubMed

ABSTRACT Scores on rating scales measuring symptoms of depression, panic anxiety, state anxiety, trait anxiety, and agoraphobic avoidance were correlated, using multivariate statistics, with total thyroxine- and thyrotropin-releasing hormone concentrations in outpatients with major depression. A significant inverse relationship was demonstrated between agoraphobic avoidance and total thyroxine concentrations in female patients. No other symptom ratings were significantly associated with these thyroid indices. The depressed patients scored in the clinically significant range for agoraphobic symptoms. Assessment of agoraphobic avoidance may help identify a clinically and biologically distinct subgroup of depressed patients.

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Keywords

agoraphobic avoidance
 
agoraphobic symptoms
 
biologically distinct subgroup
 
clinically significant range
 
depressed patients
 
female patients
 
major depression
 
multivariate statistics
 
outpatients
 
rating scales
 
significant inverse relationship
 
state anxiety
 
symptom ratings
 
symptoms
 
thyroid indices
 
thyrotropin-releasing hormone concentrations
 
total thyroxine concentrations
 
total thyroxine-