Article

Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.

Harvard University, Cambridge, Massachusetts, United States
Nature (Impact Factor: 42.35). 05/1993; 362(6422):722-8. DOI: 10.1038/362722a0
Source: PubMed

ABSTRACT Expression of globin genes in developing erythroid cells is controlled by upstream locus control regions. Activity of these regions in vivo requires an erythroid-specific nuclear factor (NF-E2) that binds AP-1-like recognition sites. Its tissue-specific component (p45 NF-E2) has been characterized by complementary DNA cloning as a new basic region-leucine zipper protein which dimerizes with a ubiquitous partner to form native NF-E2.

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Available from: Hediye Erdjument-Bromage, May 01, 2015
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