Nonresective treatment of pineoblastoma: a case report.

Division of Neurosurgery, University of Nebraska Medical Center, Omaha 68918-2035, USA.
Surgical Neurology (Impact Factor: 1.67). 11/1995; 44(4):386-903; discussion 390-1. DOI: 10.1016/0090-3019(95)00223-5
Source: PubMed

ABSTRACT Stereotactic biopsy followed by cytoreductive surgery and/or radiation are the standard treatment for pineoblastoma. We are reporting a patient with a relatively large pineoblastoma, who was treated with a combination of nonresective treatment modalities.
The patient is a 20-year-old woman who presented with signs and symptoms of raised intracranial pressure. Magnetic resonance imaging (MRI) showed a large tumor in the pineal region and hydrocephalus. She was emergently treated by placement of a ventriculoperitoneal shunt. Three days later she underwent a stereotactic biopsy, which showed the tumor to be pineoblastoma. She was then further treated with the following treatment modalities: permanent implantation of high activity I125 seeds, external radiation, and chemotherapy.
At 10 months' follow-up, MRI showed complete disappearance of the tumor. At 18 months' follow-up, the patient is asymptomatic, neurologically intact, and her MRI scans show no evidence of intracranial or intraspinal tumor.
Though the follow-up is relatively short, the results of the nonresective approach in this patient have been excellent.

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