Bone lead levels and delinquent behavior - Reply
ABSTRACT To evaluate the association between body lead burden and social adjustment.
Retrospective cohort study.
Public school community.
From a population of 850 boys in the first grade at public schools, 503 were selected on the basis of a risk scale for antisocial behavior. All of the 850 boys who scored in the upper 30th percentile of the distribution on a self-reported antisocial behavior scale were matched with an equal number drawn by lot from the lower 70% of the distribution. From this sample, 301 students accepted the invitation to participate. EXPOSURE MEASURE: K x-ray fluorescence spectroscopy of tibia at subjects' age of 12 years.
Child Behavior Checklist (CBCL), teachers' and parents' reports, and subjects' self-report of antisocial behavior and delinquency at 7 and 11 years of age.
Subjects, teachers, and parents were blind to the bone lead measurements. At 7 years of age, borderline associations between teachers' aggression, delinquency, and externalizing scores and lead levels were observed after adjustment for covariates. At 11 years of age, parents reported a significant lead-related association with the following CBCL cluster scores: somatic complaints and delinquent, aggressive, internalizing, and externalizing behavior. Teachers reported significant associations of lead with somatic complaints, anxious/depressed behavior, social problems, attention problems, and delinquent, aggressive, internalizing, and externalizing behavior. High-lead subjects reported higher scores in subjects' self-reports of delinquency at 11 years. High-lead subjects were more likely to obtain worse scores on all items of the CBCL during the 4-year period of observation. High bone lead levels were associated with an increased risk of exceeding the clinical score (T > 70) for attention, aggression, and delinquency.
Lead exposure is associated with increased risk for antisocial and delinquent behavior, and the effect follows a developmental course.
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- "1. True 2. False 9) Toxic dumping Landfills and toxic waste disposal sites are more likely to be located near African American communities than white communities. Research indicates that those sites tend to be found close to African American neighborhoods with very limited legal recourse (Barnett, 1999; Colborn, Dumanoski, & Myers, 1997; Denno, 1990; Dietrich, Succop, Berger, & Bornschein, 2001; Lynch, 2004; Lynch & Stretesky, 2001, 2003; Needleman et al., 1996; Pihl & Ervin, 1990; Pueschel, Linakis, & Anderson, 1996; Roderick, 1992; Wargo, 1998 "
ABSTRACT: Elite deviance is a complex social phenomenon whose understanding requires a modicum of knowledge about various disciplines (e.g., financial economics, accounting, politics, environmental law, etc.). Consequently, public awareness of this type of offense is expected to correlate positively with one’s general level of education. It is uncertain what other sociodemographic characteristics may be associated with knowledge about crimes of the powerful. In the present study, 408 participants completed an online questionnaire that measured (1) their sociodemographic characteristics and (2) their knowledge about elite deviance. Significant variation was found among participants in their level of knowledge about elite deviance, acceptance of “truths” and adherence to “myths” with respect to gender, race/ethnicity, education, political ideology, religious affiliation, and source of information. More knowledgeable subjects were found to be those who identified as Whites, with higher education levels, without any religious affiliation, and who used the Internet as their main source of information. In comparison, less knowledgeable participants and “myth” adherers turned out to be predominantly male, politically more conservative, Republican, conservative Protestant, and who relied on traditional media sources rather than the Internet. These findings and their implications are discussed.American Journal of Criminal Justice 10/2014; DOI:10.1007/s12103-014-9276-0
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- "The author observed an inverse tendency in periods that followed social measures to remove lead from gasoline and from the environment. Specifically, studies that explore the correlation between exposure to lead and criminality suggest a cyclical process in which exposure may lead to a lack of success in academic realms, and this in turn increases the risk of involvement in crimes (Mendelsohn, et al., 1998; Needleman et al., 1996; Nevin, 2007). Although such studies associate lead poisoning with antisocial behavior, it is not clear if the aforementioned behavior is caused directly by possible brain damage, or if it is a side effect of cognitive impairment (Lidsky & Schneider, 2006; Needleman, McFarland, Ness, Fienberg & Tobin, 2003). "
ABSTRACT: This study investigated the impact of blood lead level on intellectual (IQ) and academic performance, four years after blood contamination through lead poisoning, as well as on behavior problems and social skills, eight years after the poisoning. Fifty – four adolescents participated, with an average 14 years of age. They composed two groups: low blood lead level (less than 5 μ g/dl) and high blood lead level (greater than 10 Μ g/dl). Four years ago, participants had been assessed for social skills and behavior problems (IHSA – Del - Prette, SSRS - BR), through the WISC - III and TDE. As a result, the group with high blood lead levels presented greater IQ impairment and more behavior problems. No differences in academic performance and social skills (as evaluated by the teacher) were evidenced, but the high blood lead group assessed themselves as having a better social skills repertoire. Possible explanations and implications for these results are discussed and new questions for research are presented. Resumo: Este estudo investigou o impacto da plumbemia, quatro anos após a intoxicação, sobre o desempenho intelectual (QI) e acadêmico e, oito anos após sobre problemas de comportamento e habilidades sociais. Participaram 54 adolescentes, com idade média de 14 anos, divididos em dois grupos: com baixa plumbe mia (inferior a 5μg/dl) e com alta plumbemia (superior a 10μg/dl). Os participantes avaliados em medidas de habilidades sociais e problemas de comportamento (IHSA - Del - Prette, SSRS - BR), haviam sido avaliados, há quatro anos, com o WISC - III e o TDE. Os resultados apontaram prejuízos para o grupo com alta plumbemia no QI de Execução e em indicadores de problemas de comportamento. Não foram observadas diferenças entre os grupos quanto ao desempenho escolar e às habilidades sociais avaliadas pelo professor, porém o grupo com alta plumbemia se autoavaliou com melhor repertório de habilidades sociais. São discutidas possíveis explicações e implicações para esses resultados e novas questões de pesquisa são apresentadas.
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- "For instance, it causes neurological and neurobehavioral changes that were reported in countries with high lead pollution levels    . Among these changes, it impairs learning in experimental animals  and in humans  , and development of aggressive and delinquent behavior  that evolved in correlation with lead blood levels during preschool ages in different countries . Studies in rats had shown that chronic exposure to lead in rats induces astroglial changes in the brain and reduces dopaminergic neurons in the substantia nigra , increases brain serotonin as well as immunoreactive serotoninergic cell bodies density in the dorsal raphe nucleus, and increases in anxiety . "
ABSTRACT: Lead is a widely spread environmental pollutant known to affect both male and female reproductive systems in humans and experimental animals and causes infertility and other adverse effects. The present paper investigated the effects of prenatal exposure to lead on different parameters of estrogen stimulation in the uterus of the prepubertal rat. In prenatally and perinatally exposed rats, estrogen-induced endometrial eosinophilia, endometrial stroma edema, and eosinophil migration towards the endometrium, and uterine luminal epithelial hypertrophy are enhanced while several other responses to estrogen appear unchanged. These effects may contribute to decrease in fertility following prenatal exposure to lead. The striking difference between most of these effects of prenatal exposure and the previously reported effects of chronic exposure to lead suggests that prenatal exposure to lead may neutralize the effects of chronic exposure to lead, providing partial protection of cell function against the adverse effects of chronic exposure to lead. We propose that the mechanism involved, named imprinting or cell programming, persisted through evolution as a nongenetic adaptive mechanism to provide protection against long-term environmental variations that otherwise may cause the extinction of species not displaying this kind of adaptation.ISRN obstetrics and gynecology 01/2011; 2011:329692. DOI:10.5402/2011/329692