An Epstein-Barr virus-associated lymphoproliferative lesion of the skin presenting as recurrent necrotic papulovesicles of the face

Seoul National University, Sŏul, Seoul, South Korea
British Journal of Dermatology (Impact Factor: 4.1). 05/1996; 134(4):791-6. DOI: 10.1046/j.1365-2133.1996.99812.x
Source: PubMed

ABSTRACT We describe four patients with lymphoproliferative lesions confined to the skin for several years. They presented with recurrent necrotic papulovesicles of the face. Latent Epstein-Barr virus (EBV) infection was detected in the lymphoid cells from the skin lesions by in situ hybridization. The disease in three patients progressed to T-cell lymphoma. We believe that these patients represent a subset of peripheral T-cell lymphoma with a tendency to localize in the skin.

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