Article

The role of serotonin in the future of forensic psychiatry.

Division of Forensic of Psychiatry University of Ottawa, Ontario, Canada.
The Bulletin of the American Academy of Psychiatry and the Law 02/1996; 24(1):57-72.
Source: PubMed

ABSTRACT The role of serotonin in understanding suicidality, violence, impulse disorders, and paraphilias is described and the current state of our knowledge is reviewed. Clinical research in these areas will provide new understanding of behavior that leads to violations of the law. Forensic psychiatrists need to be more aware of these developments, and they must recognize that the uniqueness of their specialty lies in its clinical and research perspectives.

0 Bookmarks
 · 
62 Views
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Ebenso wie bislang kaum empirisch fundierte Ätiologiemodelle der einzelnen paraphilen Störungen existieren, so sind auch die neurobiologischen Grundlagen der verschiedenen Sexualpräferenzen bislang kaum verstanden.Neben einigen Hinweisen aufgrund neuropsychologischer Forschung beschränkten sich die bisherigen neurobiologischen Befunde zu sexuellen Deviationen, insbesondere die unter Nutzung moderner bildgebender Verfahren, bislang weitgehend auf Einzelfalluntersuchungen, die bspw. die Herausbildung pädophiler Neigungen in Zusammenhang mit Tumoren im Bereich des präfrontalen bzw. orbitofrontalen Kortex (OFC) gestellt haben. Neuere neurobiologische Modellvorstellungen diskutieren vor dem Hintergrund phänomenologischer Ähnlichkeiten und biologischer Korrelate der paraphilen Störungen und einer Reihe von Störungen, die zusammenfassend als Zwangsspektrumsstörungen beschrieben werden, eine Störung eines striatothalamokortikalen Netzwerkes, das viele Überschneidungen mit dem dopaminergen Belohnungssystem aufweist. Die vorliegende Übersichtsarbeit stellt die bisherigen neurobiologischen Erkenntnisse über sexuelle Abweichungen zusammenfassend dar und diskutiert am Schluss die neueren Erkenntnisse aus funktionell-bildgebenden Studien im Hinblick auf die besagte Netzwerkstörungshypothese. The etiology of existing paraphilic disorders remains poorly understood, and the neurobiological mechanisms underlying different sexual preferences are also incompletely characterized. The existing neurobiological findings examining sexual deviations, in particular studies using modern imaging techniques, are thus far limited to case studies. For instance, previous findings have associated the development of pedophilic preferences with tumors in prefrontal and orbitofrontal cortices. There are many phenomenological similarities and biological correlates between paraphilic disorders and a series of disorders summarized as obsessive compulsive spectrum disorders. For all these disorders, current neurobiological models discuss disturbances of the striato-thalamo-cortical network which overlaps with the dopaminergic reward system. This article reviews and critically discusses existing neurobiological characteristics of the sexual deviancies. To this end, it also reviews the current findings of functional imaging studies in the context of the network model.
    Forensische Psychiatrie Psychologie Kriminologie 02/2007; 1(2):139-146. DOI:10.1007/s11757-007-0022-z
  • Source
    International Journal of Law and Psychiatry 01/2002; 25(1):37-49. DOI:10.1016/S0160-2527(01)00095-4 · 1.19 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Two groups of women (one group married to sexually addicted men and the other group married to nonsexually addicted men) were compared to examine differences in family-of-origin characteristics. It was found that women married to sexually addicted men were significantly more likely to come from families-of-origin where they experienced abuse, abandonment, chaos, physical punishment, crisis, and depression. Further, these women were more likely to have families-of-origin that were rigidly disengaged. Women married to men who were not sexually addicted were more likely to come from cohesively connected families-of-origin. Implications for counseling practice are discussed.
    Sexual Addiction & Compulsivity 12/2001; 9(4):263-273. DOI:10.1080/10720160216042

Preview

Download
0 Downloads
Available from