Article

Influence of moderate daily wine consumption on body weight regulation and metabolism in healthy free-living males

Department of Exercise and Sport Science, Colorado State University, Fort Collins 80523, USA.
Journal of the American College of Nutrition (Impact Factor: 1.68). 05/1997; 16(2):134-9. DOI: 10.1080/07315724.1997.10718663
Source: PubMed

ABSTRACT Although previous studies have clearly demonstrated that energy from alcohol may not be efficiently utilized to maintain body weight when it comprises 20% or more of the daily caloric intake, there is considerable debate regarding the influence of moderate alcohol consumption (< or = 5% of the total daily caloric intake) upon metabolism, substrate utilization and body weight regulation. Consequently, the objectives of this study were to determine whether moderate alcohol consumption could influence body weight via changes in substrate utilization, oxygen consumption or alterations in dietary macronutrient content.
Fourteen male subjects (mean age = 32.1 years) participated in a 12-week, free-living, crossover trial in which they either drank red wine (270 ml; 13% v/v ethanol) daily for 6 weeks and then abstained for the next 6 weeks or vice-versa.
Whether wine was imbibed or not, no significant differences (p > 0.05) were demonstrated for any of the following variables: body weight, body fat percentage, skinfold thickness, resting metabolic rate, respiratory quotient, caloric intake, dietary macronutrient content, or fasting insulin or glucose concentrations.
In free-living subjects over a 6-week period, the addition of two glasses of red wine to the evening meal does not appear to influence any measured variable which may adversely affect body weight or promote the development of obesity during this time period.

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    • "A recent study in obese humans (The Copenhagen City Heart Study) indicated that prolonged moderate red-wine consumption (but not of other alcoholic beverages) tended to decrease abdominal obesity [6]. However, this effect has not been observed by other authors [7] [8]. "
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    • "A recent study in obese humans (The Copenhagen City Heart Study) indicated that prolonged moderate red-wine consumption (but not of other alcoholic beverages) tended to decrease abdominal obesity [6]. However, this effect has not been observed by other authors [7] [8]. "
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    • "In addition to the cross-sectional surveys, most large-scale prospective studies indicate that moderate alcohol consumption has a protective effect on the development of NIDDM (Ajani et al. 2000), but one British study (Perry et al. 1995) found a curvilinear trend between alcohol intake and the 13-year follow-up incidence of NIDDM. Experimental data on the long-term impact of alcohol on insulin sensitivity are sparse and do not support the epidemiological findings , as 6 or 10 weeks of moderate wine consumption has been reported to have no effect on fasting insulin levels or sensitivity (Cordain et al. 1997, 2000). The physiological mechanism behind the possible improvement in insulin sensitivity associated with regular moderate alcohol consumption is not obvious, and further experiments with longer intervention periods and a controlled diet should be conducted in order to establish whether the epidemiological observations reflect a true effect of alcohol, or whether they are a result of an unrecognised confounding effect of dietary (e.g. "
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