Comparison of obsessions and compulsions in patients with anorexia nervosa and obsessive compulsive disorder.
ABSTRACT Patients with anorexia nervosa (n = 18) and patients with obsessive-compulsive disorder (OCD) (n = 16) had similar scores on the Yale-Brown Obsessive Compulsive Scale (19 + or - 9 vs. 22 + or - 6). This suggests that these disorders have similar magnitude of impairment from obsessions and compulsions; however, OCD patients endorsed a wide variety of obsessions and compulsions, whereas anorexics tended to endorse symptoms that were related to symmetry and order.
SourceAvailable from: Federica Tozzi[Show abstract] [Hide abstract]
ABSTRACT: RIASSUNTO Il concetto di comorbilità, nato nell'ambito della medicina interna ed esteso poi ad ogni campo della medicina, presenta in psichiatria diverse problematiche. Applicato ai Disturbi del Comportamento Alimentare (DCA) assume un significato da chiarire. In questo lavoro è stata condotta una revisione degli studi condotti negli ultimi dieci anni sulla comorbilità dei disturbi alimentari. Cinque sono stati i modelli interpretativi pro-posti per spiegare la comorbilità dei DCA ma, alla luce dei dati raccolti in letteratura, nessuno sembra essere in grado di fornire una spiegazione esaustiva del fenomeno. Risulta invece particolarmente significativa la possibilità che i DCA rappresentino un disturbo transnosografico potendosi manifestare in tutti i disturbi psicopatologici. Le ricerche sulla comorbilità dei DCA vanno approfondite con studi di tipo longitudi-nale prospettico su campioni estesi ed omogenei. La comprensione di tale fenomeno risulterà essere particolarmente utile per sviluppare strategie terapeutiche adeguate. Parole chiave: Comorbilità, spettro, disturbi alimentari. SUMMARY The concept of comorbidity was originally used in general medicine and later applied to psychiatry to indicate the co-occurrence of different disorders in the same patient. In the area of eating disorders, the issue of comorbidity raises even more problems than in other categories of psychiatric disorders. In this paper, we critically review the literature con-cerning psychiatric comorbidity in eating disorders, with particular reference to metho-dological problems that complicate the interpretation of findings. In recent years, five theoretical models have been advanced to explain the comorbidity between eating disor-ders and other psychiatric syndromes. However, none of these models can accommodate all the data that have emerged from epidemiological studies of clinical and no clinical populations. We advance the hypothesis that disturbances of eating behaviour may reflect a dimensional phenomenon cutting across psychiatric syndromes. Prospective stu-dies conducted on large samples are needed to clarify several aspects of this important area of clinical research and to optimize therapeutic interventions in patients with eating disorders and other psychiatric syndromes.
[Show abstract] [Hide abstract]
ABSTRACT: Anorexia Nervosa (AN) is a serious psychiatric condition marked by firmly entrenched and maladaptive behaviours and beliefs about body, weight and food, as well as high rates of psychiatric comorbidity. The neural roots of AN are now beginning to emerge, and appear to be related to dysfunctional, primarily limbic, circuits driving pathological thoughts and behaviours. As a result, the significant physical symptoms of AN are increasingly being understood at least partially as a result of abnormal or dysregulated emotional processing. This paper reviews the nature of limbic dysfunction in AN, and how structural and functional imaging has implicated distinct emotional and perceptual neural circuits driving AN symptoms. We propose that top-down and bottom-up influences converge on key limbic modulatory structures, such as the subcallosal cingulate and insula, whose normal functioning is critical to affective regulation and emotional homeostasis. Dysfunctional activity in these structures, as is seen in AN, may lead to emotional processing deficits and psychiatric symptoms, which then drive maladaptive behaviours. Modulating limbic dysregulation may therefore be a potential treatment strategy in some AN patients.Cortex 01/2014; 62. DOI:10.1016/j.cortex.2014.02.020 · 6.04 Impact Factor
[Show abstract] [Hide abstract]
ABSTRACT: Not Just Right Experiences (NJREs) are considered to be a perceptually tinged phenomenon mainly related to obsessive-compulsive disorder (OCD). The evidence of an association between NJREs and OCD or OC symptoms have been accumulating in the last few years, whereas there is a paucity of studies about the role of this construct in other clinical conditions considered part of the "OCD spectrum". In the current study, the NJRE-Q-R Severity scale (a well-validated measure of NJREs) was administered to 41 patients with OCD, 53 with hair-pulling disorder (HPD), 38 with gambling disorder (GD) and 43 with eating disorders (ED) along with measures of OC symptoms and general distress. In each group, NJREs were consistently associated with OC symptoms; moreover, the pattern of associations appeared coherent with the main clinical features of each disorder. The OCD group reported higher levels of NJREs severity than GD and ED, whereas there were no differences between the OCD and HPD groups. However, HPD patients did not have higher scores of NJREs severity than GD and ED counterparts. NJREs appear to be specific to OCD, but further study is needed to establish the role of this construct in OCD-related disorders. Copyright © 2015. Published by Elsevier Ltd.Journal of Anxiety Disorders 02/2015; 31:73-83. DOI:10.1016/j.janxdis.2015.02.002 · 2.96 Impact Factor