The average prevalence of obesity (BMI > 30 kg/m2) among European centers participating in the WHO-MONICA study between 1983 and 1986 was about 15% in men and 22% in women Prevalence figures ranged in men from 7% in Gothenburg and 22% in Lithuania and in women from 9% to 45% in the same places. Some monitoring projects or repeated surveys suggest that the prevalence of obesity has been increasing during the past 15 years in some European countries. A closer look at data from The Netherlands suggest that average weight increase in the order of about 1 kilo can be responsible for quite dramatic increases in the prevalence of obesity. This suggest that only small changes in the daily caloric balance may be sufficient to increase the number of obese subjects in populations. In The Netherlands a decrease in energy intake and fat consumption was observed between 1987 and 1993 and smoking rates remained relatively stable. This could imply that reductions in energy expenditure are the main factors responsible for the increase in the prevalence of obesity. Since the increase in the prevalence of obesity seems to occur particularly in younger age-groups, the consequences of the increase in the prevalence of obesity only become apparent many years later. Especially chronic conditions such as arthritis or conditions related to obesity but occurring later in life such as cerebrovascular accidents, chronic heart failure or breast cancer in women. The rising prevalence of non-insulin dependent diabetes mellitus may be one of the first signs of the increasing problem of obesity in European countries.
"T2DM and insulin resistance are the most prominent ones. From several large prospective studies , overweight and obesity have been estimated to account for about 65%–80% of new cases of T2DM . The risk to develop DM related complications is a function of the age of onset and the duration of obesity and weight gain rate. "
[Show abstract][Hide abstract] ABSTRACT: A 32-year-old woman with type 2 diabetes mellitus suffering from morbid obesity with BMI 45,14 kg/m(2) was operated on. Not only the type 2DM but also one of its complication known as necrobiosis lipoidica diabeticorum remitted postoperatively. Obesity should no longer be regarded simply as a cosmetic problem affecting certain individuals but an epidemic that threatens global well-being. It causes or exacerbates many health problems, and in particular, it is associated with the type 2 diabetes. Necrobiosis lipoidica is a granulomatous skin disease of unknown etiology, associated mainly with diabetes mellitus. We presented in this paper a morbid obese case of necrobiosis lipoidica diabeticorum with dramatic good response to bariatric surgery.
05/2013; 2013:352579. DOI:10.1155/2013/352579
"However, it was demonstrated that smokers, especially heavy smokers tend to have higher BMIs than ligher smokers and even some nonsmokers. It was interesting that adipose tissue distrubition expressed as the waist to hip ratio showed a preponderance for abdominal sites in smokers. This may be the reason why with a normal BMI, smokers have a greater abdominal fat accumulation compared with nonsmokers. "
[Show abstract][Hide abstract] ABSTRACT: The demonstration that adipose tissue produces numerous cytokines increases interest of investigators in their role in the pathogenesis of obesity. Resistin is one of those cytokines. There are conflicing reports as cigarette smoking impairs insulin secretion, augments insulin resistance, or has no effect on glucose metabolism. In our study, we intended to examine the relationship of obesity with resistin levels in smokers and nonsmokers.
The study included 52 male smokers and 34 age matched nonsmoker male control subjects. We classified smoker and nonsmoker groups according to their body mass index as BMI < 27 and ≥27. As well as making physical and anthropometric examinations, fasting plasma glucose and insulin, postprandial plasma glucose, lipid profile, and resistin levels were measured in all male subjects. We compared all parameters in smoker and nonsmokers either having BMI < 27 or ≥27.
In both BMI levels, resistin levels were higher in smoker groups than nonsmoker ones (P<0.01 all), we did not find any difference in other parameters.
in conclusion we may speculate that if someone smokes resistin levels increase.
Journal of research in medical sciences 02/2012; 17(2):119-22. · 0.65 Impact Factor
"Our results showed that the cut-off values for sarcopenia were 6.87 and 5.46 kg m -2 in Japanese men and women, respectively, and the prevalence rates of class 1 and class 2 sarcopenia in subjects 70–85 years of age were 6.7 and 56.7% in men, and 6.3 and 33.6% in women, respectively. These values are lower than those in other ethnic groups because Japanese people are thinner than the populations of the USA and Western Europe (Flegal et al. 2002; Mokdad et al. 2003; Seidell 1997; Yoshiike et al. 2002). Table 2 Physical characteristics of adult men and women (age B 41 years) Men (age B 41 years) "
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