A persistent rise in mortality among injection drug users in Rome, 1980 through 1992

Department of Epidemiology, Lazio Region, Rome, Italy.
American Journal of Public Health (Impact Factor: 4.55). 06/1997; 87(5):851-3. DOI: 10.2105/AJPH.87.5.851
Source: PubMed

ABSTRACT The purpose of the study was to analyze overall and cause-specific mortality among injection drug users in Rome.
A cohort of 4200 injection drug users was enrolled in drug treatment centers from 1980 through 1988 and followed up until December 1992.
The age-adjusted mortality rate from all causes increased from 7.8/1000 person-years in 1985/86 to 27.7/1000 in 1991/92. The rise was mainly attributable to acquired immunodeficiency syndrome (AIDS), but mortality from overdose and other causes increased as well. The cumulative risk of death by the age of 40 was 29.3%.
The impact of AIDS deaths appears to be additional to a persistent increase of mortality for all other causes.

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Available from: Marina Davoli, Sep 29, 2015
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    • "During recent decades, the AIDS epidemic has had a major effect on this group of patients [16]. Although mortality among opioid addicts increased from 1980 to 1988 [17], this increase can only be partly explained by the emergence of AIDS [18]. Cause-specific SMRs during recent decades would be helpful in studying mortality in this group of patients. "
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    BMC Psychiatry 02/2008; 8(1):8. DOI:10.1186/1471-244X-8-8 · 2.21 Impact Factor
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    • "Data on heroin and cocaine use, overdose, mortality, crime and illegal activity have been evaluated in short-term follow-up studies [7-18]. Mortality data and substance use have been evaluated also in long-term follow-up [1,2,10,15,17,19-22]. However, few studies have assessed social rehabilitation and re-integration in mid- to long-term follow-up [15,19,23-25], and very few have evaluated the relationship between outcomes and drug abuse treatment [15,19]. "
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