Herpes zoster (shingles) affects a significant number of individuals over age 50. To date, no satisfactory treatment has been available. The clinician author (JHO) witnessed a dramatic response of a shingles patient to autohemotherapy: the pain was completely relieved and lesions gone within 5 days with no recurrence of either. Treatment of other herpetic patients then began with autohemotherapy. Twenty-five patients with herpes were given an autologous blood transfer of 10 mL of blood from the antecubital vein into the gluteal bundle and followed for clinical signs. A 100% favorable response occurred in 20 patients who received autohemotherapy within 7 weeks of the onset of clinical signs and 1 other who received autohemotherapy at a 9-week interval. No untoward signs or symptoms of the treatment occurred. Autohemotherapy has been demonstrated to be effective in elimination of clinical sequelae in these cases of herpes infections and these results justify further rigorous clinical investigation.
"This practice is as old as I because I learnt it when I was a medical student in 1953, and it positively works in improving the body's resistance to different stresses. It is used even without ozone addition as a sort of autovaccine in herpetic infections (Olwin et al., 1997). Moreover, it is currently used for treating patients with heart failure progression with the aim of reducing immune activation and inflammation, which contribute to the progression of chronic heart failure. "
[Show abstract][Hide abstract] ABSTRACT: There are a number of good experimental studies showing that exposure by inhalation to prolonged tropospheric ozone damages the respiratory system and extrapulmonary organs. The skin, if extensively exposed, may also contribute to the damage. The undoubtful strong reactivity of ozone has contributed to establish the dogma that ozone is always toxic and its medical application must be proscribed. Although it is less known, judiciously practiced ozonetherapy is becoming very useful either on its own or applied in combination with orthodox medicine in a broad range of pathologies. The opponents of ozonetherapy base their judgment on the ozone chemistry, and physicians, without any knowledge of the problem, are often skeptical. During the last 15 years, a clear understanding of the action of ozone in biology and medicine has been gained, allowing today to argue if it is true that ozone is always toxic. The fundamental points that are discussed in this paper are: the topography, anatomical and biochemical characteristics of the organs daily exposed to ozone versus the potent antioxidant capacity of blood exposed to a small and precisely calculated dose of ozone only for a few minutes. It is becoming clear how the respiratory system undergoing a chronic oxidative stress can release slowly, but steadily, a huge amount of toxic compounds able to enter the circulation and cause serious damage. The aim of this paper is to objectively evaluate this controversial issue.
[Show abstract][Hide abstract] ABSTRACT: SARS (Severe Acute Respiratory Syndrome) is a global disease of significant lethality with an expanding incidence and prevalence base. Of massive public health importance, SARS presents supremely challenging problems in light of its pathogenic capacity and mutational potential. Ozone, because of its special biological properties, has theoretical and practical attributes to make it a viable candidate as a SARS virus inactivator through a variety of physicochemical and immunological mechanisms. The Family of Coronaviruses The SARS virus belongs to the viral family Coronaviridae. which includes two genera, coronavirus and togovirus, each showing similar replication mechanisms and genomic organization but distinct genome lengths and viral architecture. First identified in the 60's, this family identifies itself by large, enveloped, positive-stranded RNA virions. Their appearance is characteristically distinct, with envelopes endowed with host cell membrane-tropic petal shaped spikes (peplomers). The large, amply spaced peplomers on the virion surface suggests a coronal (crown-like) appearance. Prior to SARS, Coronaviridae were responsible for relatively mild cold-like syndromes in humans corresponding to their predilection for the ciliary epithelium of the trachea, nasal mucosa, and alveolar cells of the lungs. At times they were only rarely implicated in serious respiratory illnesses in frail older adults (Falsey 2002). SARS represents a quantum leap in Coronaviridae infectivity by way of its significant lethality. Widely seen in nature, coronaviruses infect a spectrum of animal hosts and are responsible for avian infectious bronchitis, murine hepatitis, and porcine gastroenteritis, among others. Of possible significance to humans is that animal coronaviruses are able to penetrate into the central nervous system. SARS: Virion architecture and molecular biology The SARS virion differs from other members of the Coronaviridae family in its genomic composition. The other viral structures, however, are similar, including virion architecture, and the fundamental composition of structural and non-structural proteins. The software for viral replication is the nucleic acid core, a single strand long chain RNA nucleotide. The core is surrounded by the nucleic acid coat or capsid. The capsid is rigid and determines the shape of the virus; it is made of repeating units called capsomeres. The SARS viral nucleocapsid is tubular with a helical symmetry. The nucleocapsid is surrounded by an envelope which forms the outer layer of the virion and maintains intimate contact with host bodily fluids. As such, it is sensitive to the composition and alterations in its milieu, such as temperature, pH, and ionic balance. The viral envelope is formed at the time of budding, an intricate process in which the nucleocapsid exits the host cell. In order to do this, it fuses with the host cell membrane, appropriating its components to form its own envelope. It is known that the lipid composition of viral membranes reflects the lipid composition through which the particles exit. Viral envelopes are composed of lipid bilayers associated with a union of carbohydrates and proteins, glycoproteins, and lipids and phosphates, phospholipids. Up to 60% of the lipid component of the envelope is composed of phospholipid and the remainder is mostly cholesterol. This lipid-carbohydrate envelope is closely articulated with the peplomers which determine attachment and penetration into host
[Show abstract][Hide abstract] ABSTRACT: The science of ozone is poised to achieve major advances in medicine. Ozone, the first sentinel gaseous layer separating earth from outer space, protects life from solar electromagnetic radiation; at the same time, in the very depths of our organisms, ozone works at molecular and cellular levels to inactivate microorganism invaders via one of the most potent weapons known to biology: oxidation.
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