Congenital cystic adenomatoid malformation. Report of two cases and review of the literature.
ABSTRACT Congenital cystic adenomatoid malformation (CCAM) of the lung is a rare pulmonary lesion, characterized by an excessive overgrowth of the terminal respiratory bronchioles. The lesion is almost always unilateral and may occur in any lobe. We present two children with CCAM. The first case was a one-day-old female infant admitted with respiratory distress and cyanosis. The second case was a 19-month-old girl with a nine-month history of recurrent respiratory infections. Preoperative diagnosis of both cases was intrapulmonary mass. The histopathological examinations revealed CCAM.