Lung abscess: Pathogenesis, diagnosis and treatment

Harvard Medical School, Boston, Massachusetts, USA.
Current clinical topics in infectious diseases 02/1998; 18(18):252-73.
Source: PubMed
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    ABSTRACT: To determine whether results of physical or radiographic examination or biochemical analyses in adult racehorses with primary lung abscesses were associated with ability to race following treatment. Multiple-center retrospective study. 25 Standardbreds and 20 Thoroughbreds. Medical records of horses with a primary lung abscess that were admitted to any of 4 veterinary teaching hospitals were reviewed. Results of physical examination, laboratory testing, and thoracic radiography were reviewed. Racing performance after treatment was compared with performance before illness and with performance of the general population of racehorses of similar age, sex, and breed. 23 of 25 Standardbreds and 13 of 20 Thoroughbreds raced after diagnosis and treatment of a lung abscess. Most horses had a solitary abscess in the dorsal to caudodorsal lung fields. Results of initial physical examination, biochemical analyses, and culture and identification of the microbial isolate were not associated with whether a horse returned to racing. For horses that had raced prior to the illness, race performance after treatment of the lung abscess was not significantly different from performance before the illness. On the basis of racing performance in those horses that resumed racing after treatment, long-term residual lung damage did not develop in horses with primary lung abscesses that were treated appropriately. It is not known whether horses that recovered would be more likely to bleed from the site of a prior infection when resuming strenuous exercise and whether lung abscesses contributed to a failure to resume racing.
    Journal of the American Veterinary Medical Association 05/2000; 216(8):1282-7. DOI:10.2460/javma.2000.216.1282 · 1.56 Impact Factor
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    ABSTRACT: A 57-year-old man was hospitalized and treated for community acquired pneumonia. He was found to have radiologic evidence of a lung abscess upon completion of his oral antibiotics. Complete resolution of the abscess in a 3-month-period without any medical or surgical intervention was confirmed thereafter by repeated imaging study. Spontaneous resolution of lung abscess is possible and might be the fate of all uncomplicated lung abscesses if drainage into the tracheobronchial tree takes place early in the course. Host factors may play a role in predicting prognosis and treatment outcome.
    Clinical Pulmonary Medicine 03/2006; 13(2). DOI:10.1097/01.cpm.0000203738.76590.da
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    ABSTRACT: Lung abscesses are cavitating lesions containing necrotic debris caused by microbial infection. Patients with chronic lung disease, bronchial obstruction secondary to cancer, a history of aspiration or risk of aspiration caused by alcoholism, altered mental status, structural or physiologic alterations of the pharynx and esophagus, neuromuscular disorders, anesthesia, are among others at higher risk of developing lung abcess.The main bacteriological characteristics, the diagnosis, therapy and prognosis are considered. The problem of antimicrobial resistance is also referred.
    02/2008; 14(1):141–149. DOI:10.1016/S2173-5115(09)70248-9
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