A new strong inhibitor of beta-mannosidase

S.E.S.N.A.B., Pole Sciences et Technologie, Université de La Rochelle.
Bioorganic & Medicinal Chemistry Letters (Impact Factor: 2.33). 03/1998; 8(4):371-2. DOI: 10.1016/S0960-894X(98)00031-6
Source: PubMed

ABSTRACT N-phenyl-carbamate of D-mannonohydroxymolactone (I) was synthesized from mannose and was shown to be the best competitive inhibitor of beta-mannosidase so far reported (Ki = 25 nM).

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