Article

[House dust mite allergens and mite allergy in Copenhagen dwellings. A cross-sectional study].

Lunge- og allergiklinikken, Frederiksberg Hospital.
Ugeskrift for laeger 01/1999; 161(4):419-23. pp.419-23
Source: PubMed

ABSTRACT The aim of the study was to investigate the influence of various environmental factors on occurrence of house dust mite allergens and the influence of allergen exposure on mite allergy. Ninety-two persons from a population study filled in a questionnaire, were skin prick and lung function tested and dust samples were collected from their mattresses for analyses. Two out of five patients with asthma had a positive skin reaction to house dust mite allergen in contrast to five out of 87 non-asthmatics. Fifty-nine per cent of the dust samples contained (group 1) mite allergen > 2 micrograms/g dust. Such mattresses were older (median 7 years, range 1-22) than mattresses with less allergen (median 4 years, range 1-20). In the six bedrooms reported to be humid or mouldy, mattresses contained high concentration of mite allergens. No other parameter investigated could predict the allergen contents. In almost all cases dust analyses are crucial to be able to advise patients with house dust mite allergy.

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    Article: House dust mites and their allergens in Danish mattresses -- results from a population based study.
    Kirsten E Sidenius, Thorkil E Hallas, Lars K Poulsen, Holger Mosbech
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    ABSTRACT: The purpose of this study was to identify the level of house dust mites (HDMs) and their allergens in mattresses, not selected on their owners atopic status, and to find associated factors. Dust was collected from 68 mattresses. The recruitment was population-based and conducted during the screening phase of a HDM intervention study. The visited persons declared to have had a "cold" bedroom the previous winter. HDMs were counted and dust was analysed by ELISA for Der 1 (= Der f 1+ Der p 1+ Der m 1). Multiple regression analysis was carried out to find housing conditions associated with high HDM levels. Type of housing, mattress age and self-assessed winter bedroom-temperature explained 47% of Der 1. Median concentrations were 3.77 microg Der 1/g and 1 HDM/0.1 g dust. Both immunochemically and microscopically Dermatophagoides farinae was dominant; D. pteronyssinus less frequent but important; and D. microceras insignificant. In 62% of these suburban homes the mattress dust exceeded 2 microg Der 1/g; and measurement of both Der f 1 and Der p 1 was necessary and sufficient to evaluate HDM allergen exposure. The association with a high HDM level was highest and most consistent for one-family houses.
    Annals of agricultural and environmental medicine: AAEM 02/2002; 9(1):33-9. · 2.31 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

87 non-asthmatics
 
allergen contents
 
analyses
 
asthma
 
cases dust analyses
 
dust samples
 
group 1
 
house dust mite allergen
 
house dust mite allergens
 
house dust mite allergy
 
humid
 
mattresses
 
median 4 years
 
median 7 years
 
mite allergens
 
mite allergy
 
population study
 
positive skin reaction
 
six bedrooms