Clinical evaluation of commercially available urinary acidification diets in the management of idiopathic cystitis in cats

Waltham Centre for Pet Nutrition, Waltham-on-the-Wolds, Melton Mowbray, Leicestershire, UK.
Journal of the American Veterinary Medical Association (Impact Factor: 1.67). 03/1999; 214(3):361-5.
Source: PubMed

ABSTRACT To compare recurrence of signs of lower urinary tract disease (LUTD) in cats with idiopathic cystitis that were fed the dry or canned formulation of a commercial diet designed to result in production of an acidic urine.
Prospective trial.
54 client-owned cats with idiopathic cystitis that was diagnosed on the basis of a history of abnormal micturition, abnormal results on urinalysis, radiography, or cystoscopy, and lack of an alternative diagnosis.
Cats were assigned to be fed the canned or dry formulation of the diet. Reevaluations conducted at 2 and 16 weeks, and at 6 and 12 months included a physical examination, CBC and serum biochemical analysis (except week 2), blood gas analysis, and urinalysis. Regular telephone contacts were also made. The study was discontinued after 12 months or if signs of LUTD recurred.
Signs of LUTD did not recur in 16 of 18 cats fed the canned diet, and 17 of 28 cats fed the dry diet (chi 2, P < 0.05). Seven cats were reevaluated at recurrence. Owners of remaining cats in which signs of LUTD recurred declined to have their pets reexamined. A different problem (bacterial urinary tract infection) was identified in only 1 cat on reevaluation. Eight cats were lost to follow-up evaluation.
Feeding this commercial canned urinary acidifying diet may reduce the proportion of cats with idiopathic cystitis that will have recurrence of signs of LUTD within a 12-month period.

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    • "tions should be treated when necessary , including urinary tract obstruction , urinary tract infections , and urolith dissolution . In many cases , especially with FIC , individual episodes of LUTS are self - limiting . However , rate of LUTS recurrence within 1 yr can be as great as 40 to 50% in some feline populations ( Barsanti et al . , 1982 ; Markwell et al . , 1999 ) . The objective of this review is to discuss common medical conditions contributing to LUTS and to present currently used and potential preventative dietary modifications ."
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    • "The role of a canned diet in managing cats with idiopathic cystitis has been evaluated in two studies. In one nonrandomized prospective study of cats with idiopathic cystitis, recurrence of clinical signs occurred in 11% of cats consuming a canned food when compared with 39% of cats consuming a dry food [9]. "
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    • "Diet and exercise long have been associated with the cause, prevention, and treatment of diseases in animals. In cats, magnesium content in the diet is linked with the risk of developing feline urologic syndrome (FUS) (Buf®ngton et al., 1997; Markwell et al., 1999). Obesity can be caused by genetic factors, feeding practices (ad libitum vs. restricted feeding), food type (canned vs. dry), and/or activity level, and is associated with the development of diabetes mellitus and kidney disease in cats (Kallfelz and Dzanis, 1989; Crane, 1991; Scarlett and Donoghue, 1998a). "
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