Clinical evaluation of commercially available urinary acidification diets in the management of idiopathic cystitis in cats
ABSTRACT To compare recurrence of signs of lower urinary tract disease (LUTD) in cats with idiopathic cystitis that were fed the dry or canned formulation of a commercial diet designed to result in production of an acidic urine.
54 client-owned cats with idiopathic cystitis that was diagnosed on the basis of a history of abnormal micturition, abnormal results on urinalysis, radiography, or cystoscopy, and lack of an alternative diagnosis.
Cats were assigned to be fed the canned or dry formulation of the diet. Reevaluations conducted at 2 and 16 weeks, and at 6 and 12 months included a physical examination, CBC and serum biochemical analysis (except week 2), blood gas analysis, and urinalysis. Regular telephone contacts were also made. The study was discontinued after 12 months or if signs of LUTD recurred.
Signs of LUTD did not recur in 16 of 18 cats fed the canned diet, and 17 of 28 cats fed the dry diet (chi 2, P < 0.05). Seven cats were reevaluated at recurrence. Owners of remaining cats in which signs of LUTD recurred declined to have their pets reexamined. A different problem (bacterial urinary tract infection) was identified in only 1 cat on reevaluation. Eight cats were lost to follow-up evaluation.
Feeding this commercial canned urinary acidifying diet may reduce the proportion of cats with idiopathic cystitis that will have recurrence of signs of LUTD within a 12-month period.
- SourceAvailable from: Katherine Rose Kerr
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- "tions should be treated when necessary , including urinary tract obstruction , urinary tract infections , and urolith dissolution . In many cases , especially with FIC , individual episodes of LUTS are self - limiting . However , rate of LUTS recurrence within 1 yr can be as great as 40 to 50% in some feline populations ( Barsanti et al . , 1982 ; Markwell et al . , 1999 ) . The objective of this review is to discuss common medical conditions contributing to LUTS and to present currently used and potential preventative dietary modifications ."
ABSTRACT: Experimental and clinical investigations have confirmed the importance of dietary modifications in medical protocols designed to treat and prevent feline lower urinary tract signs (LUTS). The objective of this review is to discuss common medical conditions contributing to feline LUTS, and to present currently utilized and potential preventative dietary modifications. Feline LUTS are a set of clinical conditions with similar symptoms related to inappropriate urine elimination due to a combination of genetics, stress and frustration reactions, environment, and medical condition(s) (e.g., idiopathic cystitis, urolithiasis, urethral obstruction, and urinary tract infection). The main goals of dietary modifications to prevent LUTS are: 1) promote large dilute volumes of urine; 2) decrease the relative supersaturation of urine for specific stone types; and 3) promote healthy bacterial populations in the gastrointestinal and urogenital tracts. The impact of dietary composition, including dietary moisture, protein concentration and digestibility, mineral concentrations (i.e., Na, Cl, Ca, P, and Mg), inclusion of acidifiers and alkalinizing agents, inclusion of vitamin B6, EPA, DHA, gamma-linolenic acid, fiber concentration and characteristics, and oxalate degrading probiotics, on these outcomes is discussed, and dietary guidelines for cats are provided. Because of the complex interaction of diet composition, environment, and animal physiology, there is a need for clinical research linking current recommendations or dietary options for the treatment and prevention of LUTS with physiological outcomes (i.e., decreased RSS and LUTS recurrence). Additionally, for many recommendations (e.g., probiotic administration, EPA, DHA), extrapolation from other species was necessary. Research is needed in feline patients with LUTS on these dietary components.Journal of Animal Science 02/2013; 91(6). DOI:10.2527/jas.2012-6035 · 1.92 Impact Factor
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- "The role of a canned diet in managing cats with idiopathic cystitis has been evaluated in two studies. In one nonrandomized prospective study of cats with idiopathic cystitis, recurrence of clinical signs occurred in 11% of cats consuming a canned food when compared with 39% of cats consuming a dry food . "
ABSTRACT: Lower urinary tract disease occurs commonly in cats and is often associated with crystal-related disease. Dietary modification is beneficial in managing some of these diseases, including idiopathic cystitis, urolithiasis, and urethral matrix-crystalline plugs. Altering dietary formulation may result in decreasing urinary concentrations of crystallogenic compounds, increasing urinary concentrations fo crystallogenic inhibitors, and diluting urine composition.Veterinary Clinics of North America Small Animal Practice 12/2006; 36(6):1361-76, viii. DOI:10.1016/j.cvsm.2006.08.006 · 1.04 Impact Factor
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- "Diet and exercise long have been associated with the cause, prevention, and treatment of diseases in animals. In cats, magnesium content in the diet is linked with the risk of developing feline urologic syndrome (FUS) (Buf®ngton et al., 1997; Markwell et al., 1999). Obesity can be caused by genetic factors, feeding practices (ad libitum vs. restricted feeding), food type (canned vs. dry), and/or activity level, and is associated with the development of diabetes mellitus and kidney disease in cats (Kallfelz and Dzanis, 1989; Crane, 1991; Scarlett and Donoghue, 1998a). "
ABSTRACT: A telephone questionnaire was developed to collect information on diet, activity level, and health as part of a prior study examining long-term outcome of early-age vs. traditional-age gonadectomy in cats. The objectives of our current study were to measure the repeatability of the questionnaire through time, to describe changes in diet and activity level over a period of 1-2 years, and to determine whether current diet and activity level characteristics might influence owner ability to recall past information.A total of 100 previously interviewed cat owners completed the second administration of the telephone questionnaire. The interval between the first and second administration of the questionnaire ranged from 0.5 to 2.6 years (median=1.5 years). Owners answered multiple-choice questions related to activity level, appetite, body condition, diet type and brand (open-ended), frequency of feeding, indoor/outdoor status, and time spent outdoors. All variables measured in the questionnaire were analyzed using kappa and a 95% confidence interval. Agreement between the original and current interviews was poor for questions referring to activity level, appetite, body condition, type and brand of treats fed, and table scraps. Agreement was moderate for questions referring to brand of dry and canned foods fed, frequency of feeding, and time spent outdoors. Agreement was high for questions referring to whether dry and canned foods were fed and indoor/outdoor status. Change over time as assessed by kappa was moderate-to-high for all variables measured with the exception of whether dry diet was fed and indoor/outdoor status. Recall of all variables that changed appeared to be at least moderately influenced by current characteristics.Preventive Veterinary Medicine 10/2002; 55(2):79-94. DOI:10.1016/S0167-5877(02)00096-X · 2.51 Impact Factor