Does high soy milk intake reduce prostate cancer incidence? The Adventist Health Study (United States)
ABSTRACT Recent experimental studies have suggested that isoflavones (such as genistein and daidzein) found in some soy products may reduce the risk of cancer. The purpose of this study was to evaluate the relationship between soy milk, a beverage containing isoflavones, and prostate cancer incidence.
A prospective study with 225 incident cases of prostate cancer in 12,395 California Seventh-Day Adventist men who in 1976 stated how often they drank soy milk.
Frequent consumption (more than once a day) of soy milk was associated with 70 per cent reduction of the risk of prostate cancer (relative risk = 0.3, 95 percent confidence interval 0.1-1.0, p-value for linear trend = 0.03). The association was upheld when extensive adjustments were performed.
Our study suggests that men with high consumption of soy milk are at reduced risk of prostate cancer. Possible associations between soy bean products, isoflavones and prostate cancer risk should be further investigated.
Frontiers in Bioscience 01/2004; 9(1-3):2714. DOI:10.2741/1430 · 4.25 Impact Factor
[Show abstract] [Hide abstract]
ABSTRACT: An effective and environment-friendly method for separating and concentrating baicalin from Scutellaria Baicalensis Georgi (SBG) extract by aqueous two-phase flotation (ATPF) was established. Using an aqueous two-phase system of polyethylene glycol (PEG)/ammonium sulfate, the effects of varying solution pH, (NH4)(2)SO4 concentration in aqueous solution, PEG molecular weight, nitrogen flow rate, flotation time and initial volume of PEG phase were investigated in detail. Under the optimal conditions for ATPF, the established method was successfully applied to the real sample, and the separation efficiency was more than 90%, and the concentration coefficient was more than 27. Compared with solvent sublation (SS), liquid-liquid extraction (LLE) and aqueous two-phase extraction (ATPE), ATPF showed advantages of good separation efficiency, high concentration coefficient and low consumption of organic solvent. All experimental results indicate that ATPF is an effective pretreatment technique for the instrumental purification of baicalin from SBG. (c) 2013 Elsevier B.V. All rights reserved.Separation and Purification Technology 09/2013; 116:454-457. DOI:10.1016/j.seppur.2013.06.024 · 3.07 Impact Factor
[Show abstract] [Hide abstract]
ABSTRACT: Benign prostate hyperplasia (BPH) is a common condition affecting older men, with an incidence that is age-dependent. Histological BPH, which typically develops after the age of 40 years, ranges in prevalence from >50% at 60 years to as high as 90% by 85 years of age. Typical symptoms include increased frequency of urination, nocturia, urgency, hesitancy, and weak urine stream. Conventional medicines used for the treatment of BPH include alpha blockers and 5-alpha reductase inhibitors. This articles review the mode of action, the efficacy, and the safety, including herb-drug interactions of the most common botanicals (Serenoa repens, Pygeum africanum, Urtica dioica, and Cucurbita pepo) and nutraceuticals (isoflavones, lycopene, selenium, and β-Sitosterol) in controlling the lower urinary tract symptoms associated to BPH. Copyright © 2013 John Wiley & Sons, Ltd.Phytotherapy Research 07/2014; 28(7). DOI:10.1002/ptr.5084 · 2.40 Impact Factor