Article

Mood, neuropsychological function and cognitions in premenstrual dysphoric disorder.

Department of Psychiatry, School of Neurosciences, University of Newcastle upon Tyne.
Psychological Medicine (impact factor: 6.16). 06/1999; 29(3):727-33. pp.727-33
Source: PubMed

ABSTRACT Neuropsychological function and cognitive correlates of depression have not previously been examined in a rigorously defined population of patients suffering from premenstrual dysphoric disorder (PMDD).
MOOD, neuropsychological function and cognition were measured in 10 PMDD patients and 10 age-matched controls in both phases of the menstrual cycle in a random order, counter-balanced design.
The BDI was significantly elevated in the luteal phase of PMDD patients only while other cognitive measures showed no significant differences. Working memory was impaired in the luteal phase of the menstrual cycle with no significant differences between PMDD and control subjects.
Despite the small sample size, these results show that the BDI is sensitive to the mood fluctuations of PMDD patients. An impairment in working memory was also found although this is a general menstrual cycle effect.

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Keywords

10 age-matched controls
 
10 PMDD patients
 
BDI
 
cognitive correlates
 
counter-balanced design
 
general menstrual cycle effect
 
luteal phase
 
menstrual cycle
 
mood fluctuations
 
Neuropsychological function
 
phases
 
PMDD
 
PMDD patients
 
premenstrual dysphoric disorder
 
rigorously defined population
 
small sample size
 

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