Article

Oxidative stress induced by exercise and dietary fat modulates the coenzyme Q and vitamin A balance between plasma and mitochondria.

Department of Physiology, University of Granada, Spain.
International Journal for Vitamin and Nutrition Research (impact factor: 0.88). 08/1999; 69(4):243-9.
Source: PubMed

ABSTRACT Physical exercise induces oxidative stress. Dietary fat modulates lipid composition of plasma and fatty acid profile of mitochondrial membranes. Over 8 wk, two groups of rats were fed virgin olive oil or sunflower oil as the only fat sources. Both groups were divided into 4 subgroups according to exercise: one of sedentary rats and the other three of rats subjected to different exercises on a treadmill. There was a lower concentration of vitamin A and coenzyme Q in the plasma of animals subjected to exercise compared to the sedentary animals. The concentrations of these molecules in liver and skeletal muscle mitochondria of animals exercised until exhaustion were higher than in sedentary animals. This can suggest the existence of a balance between plasma and mitochondrial membrane for these antioxidants as a response to an oxidative attack.

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Keywords

4 subgroups
 
antioxidants
 
coenzyme Q
 
concentrations
 
Dietary fat modulates lipid composition
 
different exercises
 
exhaustion
 
fat sources
 
fatty acid profile
 
lower concentration
 
mitochondrial membranes
 
Physical exercise induces oxidative stress
 
skeletal muscle mitochondria
 
sunflower oil
 
treadmill
 
virgin olive oil