False Diagnosis of Maple Syrup Urine Disease Owing to Ingestion of Herbal Tea
University Hospital Frankfurt, Frankfurt, Hesse, GermanyNew England Journal of Medicine (Impact Factor: 55.87). 10/1999; 341(10):769. DOI: 10.1056/NEJM199909023411020
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ABSTRACT: The dramatic increase in the use of complementary and alternative medicine therapies over the past decade has led to a proliferation of resources for information on herbal medicinals and dietary supplements. During this same time period the World Wide Web was created, and we now have to contend with yet another method of information dissemination. More than ever, clinical practitioners need to be able to differentiate between biased or unscientific information and reliable, evidence-based information. In this overview, we provide a comprehensive, annotated listing of reliable resources of information on herbs and dietary supplements divided into the following categories: journals, databases and Web sites, and books and compendia.Journal of Herbal Pharmacotherapy 12/2000; 1(1):35-61. DOI:10.1300/J157v01n01_05
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ABSTRACT: In many countries, uses of fenugreek (Trigonella foenum graecum L.) are numerous, in culinary preparations as well as in human and veterinary medicine. This annual legume, traditionally cultivated in Europe, Africa and Asia, is a popular food, consumed in various ways. For example, ground seeds which are highly flavoured are used in spice mixtures, mainly in curries; young seedlings and other portions of fresh plant material are eaten as vegetables; powder or flour of the grain is utilized as a supplement in home-baked bread; raw seeds are used to brew a hot beverage, or are eaten boiled in water, roasted after germination for 2-3 days, etc. Moreover, both the fresh green shoots and the seeds of fenugreek are used in cattle feeding. Fenugreek seeds contain high levels of proteins rich in lysine, and lipids (> 5%) constituting an important source of polyunsaturated (linoleic and linolenic) fatty acids. Carbohydrates representing over 50% of the dry matter are almost devoid of nutritional interest. Storage carbohydrates in the dry seed, mainly galactomannans contained within the endosperm cell walls, exhibit interesting emulsifying properties. Concerning fenugreek as a food source of minerals and vitamins, the seeds contain high amounts of iron and germination of the fenugreek improves its vitamins A, B and C content. 4-hydroxyisoleucine, a peculiar free amino acid extracted from seeds potentiates an insulinotropic activity through a direct effect on pancreatic B cells in rats and humans. Consumption of the seed also results in a hypocholesterolemic effect due to the presence of steroidal saponins the aglycons sapogenins which can be used for the steroid synthesis. As for others leguminous plants, dormant seed has been reported to contain anti-nutritional factors, more particularly human and bovine trypsin and chymotrypsin inhibitors and trigonelline, which is convertible into niacin during the roasting of grain. Finally, although fenugreek seed does not constitute a basic foodstuff, it is generally recognized as safe for human consumption as a spice or natural seasoning and as a plant extract.Sciences des Aliments 01/2001; 21(1):3-26. · 0.04 Impact Factor
- Sciences des Aliments 02/2001; 21(1):3-26. DOI:10.3166/sda.21.3-26 · 0.04 Impact Factor
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