Panic attacks and suicide attempts in mid-adolescence.
ABSTRACT The aim of this study was to investigate the association of panic attacks and suicide attempts in a community-based sample of 13-14-year-old adolescents.
The data are from a survey of 1,580 students in an urban public school system located in the mid-Atlantic region of the United States. Logistic regression methods were used to estimate associations between panic attacks and suicidal ideation and suicide attempts.
Controlling for demographic factors, major depression, the use of alcohol, and the use of illicit drugs, the authors found that adolescents with panic attacks were three times more likely to have expressed suicidal ideation and approximately two times more likely to have made suicide attempts than were adolescents without panic attacks.
This new epidemiologic research adds to the evidence of an association between panic attacks and suicide attempts during the middle years of adolescence.
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- "A comprehensive clinical evaluation was conducted and some features were investigated using innovative assessment instruments (e.g. the Dimensional Yale–Brown Obsessive–Compulsive Scale to evaluate the presence and severity of OCD symptom dimensions and the USP-Sensory Phenomena Scale to assess sensory phenomena). Given that the literature usually reports PD/AG findings together, we could only hypothesize that OCD patients with comorbid PD/AG, compared to those without PD/AG would: (1) be more frequently female  and more impaired, as indicated by lower educational, occupational and socioeconomic levels   ; (2) present greater clinical severity, including obsessive–compulsive, anxious and depressive symptoms   and more suicidal thoughts and attempts       ; (3) present more aggressive symptoms  and comorbidity with depressive    and bipolar disorders    , other anxiety disorders   , hypochondriasis   , somatization disorder , tic disorders  and substance use disorders  "
ABSTRACT: Panic Disorder (PD) and agoraphobia (AG) are frequently comorbid with obsessive-compulsive disorder (OCD), but the correlates of these comorbidities in OCD are fairly unknown. The study aims were to: 1) estimate the prevalence of PD with or without AG (PD), AG without panic (AG) and PD and/or AG (PD/AG) in a large clinical sample of OCD patients and 2) compare the characteristics of individuals with and without these comorbid conditions. A cross-sectional study with 1001 patients of the Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders using several assessment instruments, including the Dimensional Yale-Brown Obsessive-Compulsive Scale and the Structured Clinical Interview for DSM-IV-TR Axis I Disorders. Bivariate analyses were followed by logistic regression models. The lifetime prevalence of PD was 15.3% (N=153), of AG 4.9% (N=49), and of PD/AG 20.2% (N=202). After logistic regression, hypochondriasis and specific phobia were common correlates of the three study groups. PD comorbidity was also associated with higher levels of anxiety, having children, major depression, bipolar I, generalized anxiety and posttraumatic stress disorders. Other independent correlates of AG were: dysthymia, bipolar II disorder, social phobia, impulsive-compulsive internet use, bulimia nervosa and binge eating disorder. Patients with PD/AG were also more likely to be married and to present high anxiety, separation anxiety disorder, major depression, impulsive-compulsive internet use, generalized anxiety, posttraumatic stress and binge eating disorders. Some distinct correlates were obtained for PD and AG in OCD patients, indicating the need for more specific and tailored treatment strategies for individuals with each of these clinical profiles.Comprehensive psychiatry 11/2013; DOI:10.1016/j.comppsych.2013.11.017 · 2.26 Impact Factor
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- "Psychiatric disorders are a major risk factor for youth suicide. Studies have shown that 70–91% of community-based youths who have experienced suicidal ideation or attempted suicide have a psychiatric disorder (Fergusson & Lynskey 1995, Gould et al. 1998), such as mood disorders, anxiety, disruptive behaviour or substance use, which have been identified as risk factors (Andrews & Lewinsohn 1992, Lewinsohn et al. 1994, 1995, Reinherz et al. 1995, Gould et al. 1998, Pilowsky et al. 1999). The Children's Depression Inventory (CDI) was used to identify a high-depression-risk community group. "
ABSTRACT: This paper is a report of a study conducted to develop a Chinese version of the Positive and Negative Suicide Ideation Inventory and evaluate its psychometric properties. Comprehensive assessment of suicidal behaviour in youths should incorporate both protective factors and risk factors. We recruited 2341 middle- and high-school students for a longitudinal and prospective study, conducted between 2005 and 2007. To assess predictive validity, a convenience sample of 251 of the 2341 students was recruited 1 year later to follow-up on suicide attempts during the preceding 2 weeks. To evaluate construct validity, a small convenience sample of 94 adolescent inpatients and outpatients was used as a comparison group. Instruments used included the Children's Depression Inventory, the Self-Control Schedule, and the Cognitive Triad for Children. Cronbach's alpha coefficients for the Chinese version of the positive and negative suicide ideation-negative suicide ideation and the Chinese version of the positive and negative suicide ideation-positive ideation were 0.94 and 0.86 respectively. Satisfactory test-retest reliability was evident. Convergent and divergent validities were demonstrated by statistically significant correlations among subscales and the other instruments used. Construct validity was evidenced by statistically significantly different scores on the subscales among the contrasted groups. Subscale scores in the first-wave study statistically significantly predicted attempted suicide behaviour 1 year later, demonstrating evidence of predictive validity. Factor analysis showed a two-factor structure. The Chinese Version of the Positive and Negative Suicide Ideation Inventory may be a reliable and valid instrument to measure the severity of suicidal ideation in adolescents, subject to further research to test the generalizability of the present findings.Journal of Advanced Nursing 05/2009; 65(7):1485-96. DOI:10.1111/j.1365-2648.2009.05005.x · 1.69 Impact Factor
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- "Although an association between PD and suicidal ideation has been reported in community samples [Pilowsky et al., 1999; Weissman et al., 1989], most studies that use psychiatric samples (i.e., treatmentseeking adults recruited in psychiatric clinics and hospitals) do not find a statistically significant association independent of comorbid mental disorders [e.g., Beck et al., 1992; Friedman et al., 1993, Warshaw et al., 2000]. For example, Warshaw et al.  reported that there was no association between PD and suicidal ideation after controlling for common comorbid psychiatric disorders (n 5 498). "
ABSTRACT: The purpose of this study was to ascertain whether panic disorder (PD) and suicidal ideation are associated in an inner-city primary care clinic and whether this association remains significant after controlling for commonly co-occurring psychiatric disorders. We surveyed 2,043 patients attending a primary care clinic using the Primary Care Evaluation of Mental Disorders (PRIME-MD) Patient Health Questionnaire, a screening instrument that yields provisional diagnoses of selected psychiatric disorders. We estimated the prevalence of current suicidal ideation and of common psychiatric disorders including panic disorder and major depression. A provisional diagnosis of current PD was received by 127 patients (6.2%). After adjusting for potential confounders (age, gender, major depressive disorder [MDD], generalized anxiety disorder, and substance use disorders), patients with PD were about twice as likely to present with current suicidal ideation, as compared to those without PD (adjusted odds ratio [AOR] = 1.84; 95% confidence interval [CI]: 1.06-3.18; P = .03). After adjusting for PD and the above-mentioned potential confounders, patients with MDD had a sevenfold increase in the odds of suicidal ideation, as compared to those without MDD (AOR = 7.00; 95% CI: 4.42-11.08; P < .0001). Primary care patients with PD are at high risk for suicidal ideation, and patients with PD and co-occurring MDD are at especially high risk. PD patients in primary care thus should be assessed routinely for suicidal ideation and depression.Depression and Anxiety 01/2006; 23(1):11-6. DOI:10.1002/da.20092 · 4.29 Impact Factor