Article

Lobular carcinoma of the breast metastatic to the oral cavity mimicking polymorphous low-grade adenocarcinoma of the minor salivary glands.

Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1072, USA.
Archives of pathology & laboratory medicine (Impact Factor: 2.88). 02/2000; 124(1):157-9. DOI: 10.1043/0003-9985(2000)124<0157:LCOTBM>2.0.CO;2
Source: PubMed

ABSTRACT The oral cavity is a rare site of metastatic lesions; however, metastatic breast carcinoma must be included in the differential diagnosis of tumors of that site in women. We describe a 54-year-old woman who presented with a lesion of the floor of the mouth that histologically resembled polymorphous low-grade adenocarcinoma of the minor salivary glands, which was eventually established to represent metastatic lobular breast carcinoma. The final diagnosis was based on comparison with a primary tumor resected 13 years earlier and immunohistochemical reactivity with antibodies to steroid receptors. Relevant aspects of lobular breast carcinoma, polymorphous low-grade adenocarcinoma, and metastatic oral cavity lesions are discussed.

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