Peliosis hepatis in a dog infected with Bartonella henselae.

Department of Clinical Science, College of Veterinary Medicine, University of Illinois, Urbana 61801, USA.
Journal of the American Veterinary Medical Association (Impact Factor: 1.67). 03/2000; 216(4):519-23, 517. DOI: 10.2460/javma.2000.216.519
Source: PubMed

ABSTRACT A 6-year-old spayed female Golden Retriever was examined because of generalized weakness and abdominal distention. Abdominal ultrasonography revealed a large quantity of peritoneal fluid. In addition, the liver appeared larger than normal and contained multiple, small, nodular masses and cyst-like structures. Abdominal exploratory surgery was performed, and 5 L of serosanguineous peritoneal fluid was removed. Gross lesions were not found in the stomach, kidneys, intestines, adrenal glands, or urinary bladder. There were diffuse cystic nodules in all liver lobes. The dog did not recover from anesthesia. A diagnosis of peliosis hepatis was made on the basis of gross and histologic appearance of the liver. A polymerase chain reaction assay revealed Bartonella henselae DNA in liver specimens. To our knowledge, this is the first report of molecular evidence of B henselae infection in a dog with peliosis hepatis.

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    ABSTRACT: Cat Scratch Disease (CSD) is an important zoonosis seen in cats and a public health problem in all over the world. In this study, prospective cross-sectional serologic survey and examination of local health authority records for CSD, the seroprevalence of antibodies against Bartonella henselae in pet and stray cats, and its public health aspect were investigated. Total antibodies to B. henselae were evaluated by indirect fluorescent antibody test (IFAT) in serum samples taken from 93 pet cats and 93 stray cats from the Selcuk University Veterinary Faculty Animal Hospital and Konya Municipality Stray Animal Shelter. Percentages of pet cats and stray cats seropositive for antibodies against Bartonella henselae (26.88% and 41.94%, respectively) were significantly higher than percentages of pet cats. Total seroprevalence of Bartonella henselae was found to be 34.41% in the study. A total of 438 CSD cases were identified in the Konya region according to the data received from local health authority records in the previous 1.5 years (2011-2012). Stray cats have higher seroprevalences of antibodies against Bartonella henselae, but this likely was related to greater exposure to vectors of these organisms. In conclusion, it was observed that CSD is an important risk for public health in Konya region. Therefore in order to decrease CSD prevalence in this region and prevent transmission of the disease to humans, information, treatment and prevention studies must be carried out within the One Health concept. Halk Sağlığı Açısından Pet ve Başıboş Kedilerde Bartonella henselae Prevelansı: Tek Tıp-Tek Sağlık Konseptinde Örnek Bir Çalışma Özet Kedi tırmık hastalığı (Cat Scratch Disease, CSD), kedilerde görülen ve bütün dünyada halk sağlığı problemi olan önemli bir zoonozdur. Bu çalışmada, prospektif kesitsel tarama ile pet ve başıboş kedilerdeki Bartonella henselae antikorlarının seroprevalansı ve bölge sağlık kuruluşlarının CSD kayıtları üzerinden hastalığın halk sağlığı açısından durumu araştırıldı. Total B. henselae antikorları, Selçuk Üniversitesi Veteriner Fakültesi Hayvan Hastanesi ve Konya Büyükşehir Belediyesi Geçici Hayvan Bakımevi'nden 93 pet ve 93 başıboş kediden alınan serum örneklerinde indirekt flörosan antikor testi (IFAT) ile değerlendirildi. B. henselae seropozitifliği pet ve başıboş kediler (sırasıyla, %26.88 ve %41.94) arasında yapılan karşılaştırmada, başıboş kedilerde belirgin şekilde yüksekti. Çalışmada, B. henselae' nın total seroprevalansı %34.41 olarak bulundu. Bölge sağlık örgütlerinin 1.5 yıllık (2011-2012) kayıtlarına göre Konya bölgesinde toplamda 438 CSD vakası görüldüğü tespit edildi. Başıboş kedilerde B. henselae seroprevalansının yüksek olması, başıboş kedilerin vektörlerle yoğun temasta olmalarına yorumlandı. Sonuç olarak, Konya bölgesinde CSD'nin halk sağlığı açısından önemli bir risk olduğu gözlendi. Bu çerçevede bölgedeki CSD prevalansını azaltmak ve insanlara geçişini önlemek için tek sağlık konsepti içerisinde bilgilendirme, tedavi ve koruma çalışmaları yapılması gerektiği sonucuna varıldı.
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    ABSTRACT: Peliosis hepatis (PH) is a rare benign liver lesion, characterized by the presence of multiple blood‐filled cavities and marked dilation of the hepatic sinusoids throughout the hepatic parenchyma. It is often confirmed after the liver resection or liver biopsy. In the present study, we report a case of a 41‐year‐old woman who presented with a asymptomatic right hepatic mass. The imaging findings of the mass, including computed tomography and magnetic resonance imaging, showed centrifugal progression of enhancement during the portal and delayed phases. Because of the possibility of hepatic malignancy, partial resection of the liver was performed. The final pathological diagnosis was PH. By referring to the relevant literature, we conclude that, as a result of insignificant clinical manifestation and imaging features, PH should be kept in mind for patients with hepatic mass.
    Surgical Practice 08/2013; 17(3). DOI:10.1111/j.1744-1633.2012.00640.x · 0.17 Impact Factor
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    ABSTRACT: Peliosis hepatis (PH) is a rare condition characterized by the presence of blood-filled cavities within the liver. The etiology of PH remains unknown, but it has been reported to be associated with infections or malignancies. However, the cause of PH is not clear in 20-50% of patients. The current study presents the case of a 19-year-old male who presented with right upper quadrant pain that had lasted for three days. The patient was a student with no previous medical history. Contrast-enhanced computer tomography (CT) and ultrasonography showed a neoplasm in the right liver and a diagnosis of primary liver cancer was made due to the manifestation of the disease and the results of physical tests. The individual was treated successfully with an irregular right hemihepatectomy and was in good health at 6-months post-surgery. A tissue specimen was obtained and determined to be PH by pathological examination and immunohistochemistry analysis. Consequently, a diagnosis of PH must be considered in cases like this.
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