Blastomatous tumor with teratoid features of nasal cavity: Report of a case and review of the literature

Department of Pathology, Gülhane Military Medical Academy, School of Medicine, Ankara, Turkey.
Pathology International (Impact Factor: 1.69). 02/2000; 50(1):71-5. DOI: 10.1046/j.1440-1827.2000.01012.x
Source: PubMed


A case of blastomatous tumor with teratoid features is presented. The polypoid mass was observed in the left nasal cavity of a 72-year-old man. Histologically, the lesion was composed of neuroepithelial cells with blastomatous appearance, cystic squamous nests filled with keratin materials, many mucous glands, complex tubular and glandular structures with edematous fibroblastic stroma. Sinonasal neoplasms including teratoid components and immature neuroepithelium are exceedingly rare. We suggest that the term 'immature teratoma' is more suitable than blastoma or blastomatous tumor when there is no carcinomatous or sarcomatous component besides the immature neuroepithelium and teratoid elements.

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    • "Because of its heterogeneous composition, the diagnosis of SNTCS can be quite challenging, particularly if the sampling is not sufficient. Other tumors that may be considered include primarily olfactory neuroblastoma, squamous cell carcinoma, adenocarcinoma, neuroendocrine carcinoma, sarcoma, blastomatous tumors with teratoid features, and craniopharyngeoma [3,33,34]. One feature that seems to be highly suggestive of SNTCS is the presence of the "fetal-appearing" clear cell squamous epithelium [35]. "
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