"However, most AMPs are found high amount in plant seeds and some of these peptides were isolated for molecular, biochemical as well as structural studies (Odintsova et al., 2007). Members of the family Solanaceae are shown to have the growth inhibition ability toward bacteria, fungi and virus (Chah et al., 2000; Arthan et al., 2002; Wiart et al., 2004). "
[Show abstract][Hide abstract] ABSTRACT: Solanum stramonifolium Jacq. fruit is a commonly found vegetable and herb in Thailand. Its seed aqueous extract was investigated for antibacterial activity by disc diffusion method, protein profile and protein purification. Its seed aqueous extract showed very good inhibition against pathogenic bacteria both gram positive including Stapyllococcus aureus, Bacillus licheniformis, B. subtilis and Xanthomonas sp. and gram negative bacteria including Pseudomonas aeruginosa and Salmonella typhi. Tris-tricine SDS-PAGE revealed major protein bands approximately 10.2, 15.7 and 21.5 kDa. Partial purification by Hitrap Q XL and SOURCE 15RPC column chromatography revealed that the active proteins might bear negative charges. A strong antibacterial activity suggests this plant species could be a good source for antibacterial agents. Further works on pure active compounds characterizations such as molecular structure and bacterial killing mechanism are still needed.
International Journal of Agriculture and Biology 01/2012; · 0.90 Impact Factor
"Solanum torvum (family Solanaceae) also known as 'top na aka' in the Batoufam language, is a plant used in Cameroonian folk medicine for the treatment of fever, wound healing and tooth decay . It is reported to have anti-microbial, anti-viral [26,27] and haemostatic properties . A study carried out in Peru on 510 plants showed that 11 species were identified for the treatment of infection, 59 species had anti-inflammatory properties and 43 were used to treat wounds and had haemeostatic properties . "
[Show abstract][Hide abstract] ABSTRACT: The extraction of the teeth by traditional healers in Cameroon is an established cultural practice in the central region of the Cameroon. Traditional healers (TH) use herbs and crude un-sterilized instruments and tools for the tooth extraction procedure. The present study investigates the knowledge and practices of traditional healers regarding tooth extraction and the management of its complications.
A cross sectional design utilizing semi-structured questionnaires was used to collect the data from traditional healers and their patients.
Sixteen traditional healers (TH) were interviewed. All were male and the majority were between 25-35 years old. The most important reason given for the removal of a tooth was "if it has a hole". All reported using herbs to control bleeding and pain after extractions. Only 20% used gloves between patients when extracting a tooth and just over a third (31.3%) gave post-operative instructions. Eighty seven percent managed complications with herbs and 62.5% reported that they would refer their patients to a dentist whenever there are complications. Only a third (31.3%) was familiar with the basic anatomy of a tooth and more than half (56.3%) reported that tooth extractions are the only treatment for dental problems.One hundred and fifty patients were interviewed with a mean age of 29 years. More than two thirds were in the 21-30 year age group and just over half were male. Sixty six percent reported that they visited the TH because it is cheap, 93.3% were satisfied with the treatment they received while 95.3% reported said they never had a problem after an extraction.
Tooth extractions using medicinal plants is well established in Lekie division, Cameroon. Infection control during extraction is not the norm. Traditional healers are willing to co-operate with oral health workers in improving the oral health of their patients. Mutual cooperation, collaboration and integrating TH into primary oral health care services need to be increased.
Journal of Ethnobiology and Ethnomedicine 05/2011; 7(1):15. DOI:10.1186/1746-4269-7-15 · 2.00 Impact Factor
"Solanum torvum Swartz, a folk herbal medicine, is used as sedative , digestive, haemostatic and diuretic in the south areas of China . Pharmacological studies on this plant have demonstrated cytotoxic activities , antimicrobial  , and antiviral activity . Although many steroidal glycosides such as trovonin A , trovonin B  and torvosides A-L [5,8,9] have been isolated from the plant, few bioactivities have been reported. "
[Show abstract][Hide abstract] ABSTRACT: Two novel C-22 steroidal lactone saponins, namely solanolactosides A, B (1, 2) and two new spirostanol glycosides, namely torvosides M, N (3, 4) were isolated from ethanol extract of aerial parts of Solanum torvum. Their structures were characterized as solanolide 6-O-[alpha-l-rhamnopyranosyl-(1-->3)-O-beta-d-quinovopyranoside] (1), solanolide 6-O-[beta-d-xylopyranosyl-(1-->3)-O-beta-d-quinovopyranoside] (2), yamogenin 3-O-[beta-d-glucopyranosyl-(1-->6)-O-beta-d-glucopyranoside] (3) and neochlorogenin 3-O-[beta-d-glucopyranosyl-(1-->6)-O-beta-d-glucopyranoside] (4) on the basis of spectroscopic analysis. The cytotoxicities of the saponins (1-4) were evaluated in vitro against a panel of human cancer cell lines. Compounds 3 and 4 showed significant cytotoxic activity with the cell lines.
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