Noninvasive monitoring of nonshunted pulmonary capillary blood flow in the acute respiratory distress syndrome.

Abstract

Noninvasive monitoring of nonshunted pulmonary capillary blood flow, using the alveolar amplitude response technique (AART) in a porcine model of the acute respiratory distress syndrome.
Experimental animal study.
University center for animal experiments.
In 12 mechanically ventilated pigs, the nonshunted pulmonary capillary blood flow was varied by means of lung lavages and the application of positive end-expiratory pressure.
Nonshunted pulmonary capillary blood flow was determined by AART. Cardiac output (determined by the thermodilution method) corrected for venous admixture was used for comparison (r2 varied between .58 and .94; p < .01). The trend in the development of nonshunted pulmonary capillary blood flow as measured with AART was in agreement with the trend detected by cardiac output corrected for venous admixture in 92% of all events.
We conclude that AART can be used to monitor changes in nonshunted pulmonary capillary blood flow in cases of acute respiratory distress syndrome noninvasively and continuously.

Full text

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Non-invasive respiratory monitoring in surgical intensive care

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ISBN: 90-77017-26-7
Cover: Esther Dijkstra
Printed by Optima Grafische Communicatie, Rotterdam
This thesis was financially supported by the Bronovo Research Fund and Byk Nederland.
©J.K.K Kanhai. No part of this thesis may be reproduced, stored in a retrieval system of
any nature, or transmitted in any form by any means, electronic, mechanical,
photocopying, recording or otherwise, included complete or partial transcriptions, without
the permission of the author.

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Non-invasive respiratory monitoring in surgical intensive care
Niet-invasieve respiratoire bewaking in chirurgiscbe intensive care
Proefscbrift
Ter verkrijging van de graad van doctor aan de
Erasmus Universiteit Rotterdam
op gezag van de
Rector Magnificus
Prof.dr.ir. J.H. van Bemmel
en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op
donderdag 29 november 2001 om 16.00 uur
door
Karansingh Joy Krishnamoertisingh Kanhai
geboren te Paramaribo, Suriname

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Promotiecommissie
Promotor:
Overige leden:
Prof.dr. B.A. Bruining
Prof.dr. J.M. Bogaard
Prof.dr. C. !nee
Dr.ir. G.J. Puppels
Paranimfen: Steven Buijk
Jasper van Bommel

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To my parents