Ethanol-glycine irrigating fluid for transurethral resection of the prostate in practice

Departments of Urology and Anaesthesia, Weston General Hospital, Weston-super-Mare, UK.
BJU International (Impact Factor: 3.53). 08/2000; 86(1):43-6. DOI: 10.1046/j.1464-410x.2000.00733.x
Source: PubMed


To evaluate the usefulness of a tracer of 1% ethanol in 1. 5% glycine in the early detection of irrigation fluid absorption during transurethral resection of the prostate (TURP).
Patients (120) undergoing TURP were irrigated with 1% ethanol in 1.5% glycine solution and their expired air tested for alcohol every 10 min during the procedure.
In all, 112 patients were assessed; over half of the patients absorbed the irrigation fluid and they had a significantly lower postoperative serum sodium concentration (P < 0.002). Fourteen patients (12.5%) absorbed over 500 mL and two (1.8%) developed clinical features of the TUR syndrome. The experience of the surgeon, the weight of resected chips and the operative duration were not significantly predictive of absorption.
A tracer amount of ethanol in the irrigant is reliable for detecting absorption. Irrigating fluid absorption was unpredictable, thus supporting the case for routine monitoring.

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    • "With a pulse duration of 250 to 350 m, the vapor bubble is pear-shaped and collapses asymmetrically with weak cavitation and minimal plasma formation producing a primarily photothermal effect.[20–22] A number of studies done have shown advantages of laser over conventional TURP including decreased postoperative irrigation, less postoperative catheter time, shorter hospital stay, less hematuria, and discomfort.[2324] No studies however are available, comparing fluid absorption between these two modalities to the best of our knowledge. "
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    ABSTRACT: We conducted a study to detect, quantify and compare irrigation fluid absorption in transurethral resection of the prostate (TURP) and Holmium laser enucleation of the prostate (HoLEP), using BEC. The study included 50 patients of lower urinary tract symptoms, secondary to benign enlargement of prostate. The patients were nonrandomly allocated to undergo TURP and HoLEP. Twenty-six patients underwent TURP and the remaining 24 underwent HoLEP. Sterile water tagged with 1% ethanol w/v was used for irrigation. Absorption was detected and quantified every 10min by BEC levels. Data was analyzed using standard nomograms. In HoLEP, 14/24 had no fluid absorption. The remaining 10/24 showed fluid absorption ranging from 95 ml to 300 ml. In TURP, all had fluid absorption ranging from 250-980 ml. Three TURP patients developed overt symptoms, while none did in the HoLEP group. Fluid absorption observed in our study in the HoLEP group was lower than in the TURP group.
    Indian Journal of Urology 05/2007; 23(2):126-9. DOI:10.4103/0970-1591.32061
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    BJU International 12/2001; 88(7):804. DOI:10.1046/j.1464-410X.2001.00169-3.x · 3.53 Impact Factor
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    ABSTRACT: A literature search was performed for articles between June 2000 and July 2001 pertaining to transurethral resection of the prostate. Eight of the most interesting and/or groundbreaking articles, as deemed by the authors, were selected for review. Topics discussed include transurethral vaporization of the prostate, laser prostatectomy, preoperative finasteride, pelvic floor rehabilitation, the impact of the quantity of tissue removed, bladder infusion prior to catheter removal, and ethanol-glycine in assessment of the absorption of irrigation fluid.
    Current Opinion in Urology 02/2002; 12(1):19-23. DOI:10.1097/00042307-200201000-00005 · 2.33 Impact Factor
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