Ethanol-glycine irrigating fluid for transurethral resection of the prostate in practice

Departments of Urology and Anaesthesia, Weston General Hospital, Weston-super-Mare, UK.
BJU International (Impact Factor: 3.13). 08/2000; 86(1):43-6. DOI: 10.1046/j.1464-410x.2000.00733.x
Source: PubMed

ABSTRACT To evaluate the usefulness of a tracer of 1% ethanol in 1. 5% glycine in the early detection of irrigation fluid absorption during transurethral resection of the prostate (TURP).
Patients (120) undergoing TURP were irrigated with 1% ethanol in 1.5% glycine solution and their expired air tested for alcohol every 10 min during the procedure.
In all, 112 patients were assessed; over half of the patients absorbed the irrigation fluid and they had a significantly lower postoperative serum sodium concentration (P < 0.002). Fourteen patients (12.5%) absorbed over 500 mL and two (1.8%) developed clinical features of the TUR syndrome. The experience of the surgeon, the weight of resected chips and the operative duration were not significantly predictive of absorption.
A tracer amount of ethanol in the irrigant is reliable for detecting absorption. Irrigating fluid absorption was unpredictable, thus supporting the case for routine monitoring.

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