Adhesion signaling: PAK meets Rac on solid ground

The Picower Institute for Medical Research, Manhasset, NY 11030, USA. .
Current Biology (Impact Factor: 9.92). 08/2000; 10(14):R535-7. DOI: 10.1016/S0960-9822(00)00588-1
Source: PubMed

ABSTRACT Interaction of cells with the extracellular matrix influences various aspects of cellular behavior. A recent study shows that cell-substrate adhesion is necessary for effective coupling of the small GTPase Rac to its effector PAK.

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