Gluten-dependent diabetes-related and thyroid-related autoantibodies in patients with celiac disease

Università di Pisa, Pisa, Tuscany, Italy
Journal of Pediatrics (Impact Factor: 3.74). 09/2000; 137(2):263-5. DOI: 10.1067/mpd.2000.107160
Source: PubMed

ABSTRACT Patients with celiac disease are at high risk of having autoimmune disorders. Moreover, untreated patients with celiac disease have been found to have a higher than expected prevalence of organ-specific autoantibodies. In a prospective study of 90 patients with celiac disease, we found that the prevalence of diabetes and thyroid-related serum antibodies was 11.1% and 14.4%, respectively. Like antiendomysium autoantibodies, these organ-specific antibodies seem to be gluten-dependent and tend to disappear during a gluten-free diet.

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