Ceramics in orthopaedics.

H pital Lariboisière and the Laboratoire de Recherches Orthopédiques, Paris, France.
Journal of Bone and Joint Surgery - British Volume (Impact Factor: 2.69). 12/2000; 82(8):1095-9. DOI: 10.1302/0301-620X.82B8.11744
Source: PubMed
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    ABSTRACT: Development of bioorganic–inorganic composites has drawn eyes to extensive attention in biomedical fields and tissue engineering. So many attempts to prepare hydroxyapatite (HA), in conjunction with various binders including polyvinyl alcohol (PVA), and collagen has performed for late 20 years. We applied a method based on the phase separation for making of polymer porous membranes. This procedure is induced through the addition of a small quantity of water (polymer-rich phase) to a solution with HA precursors (polymer-poor phase). Thermal and structural composite properties of collagen Hydrolysate (CH)–PVA/HA Polymer-Nano-Porous Membranes were analyzed by Design of experiment that was undertaken using D-optimal approach, to select the optimal combination of nano composites precursor. The resulted composite characters were investigated by Fourier transform infrared, scanning electron microscopy (SEM) and thermal gravimetric analysis. Based on the SEM images, this new method could be clearly concluded to porous CH–PVA/HA hybrid materials. Finally the hemocompatibility of nanocomposite membranes were evaluated by the hemolysis study. Graphical Abstract
    Systems and Synthetic Biology 12/2013;
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    ABSTRACT: A ceramic femoral head is an alternative to a metal femoral head for the bearing surface of total hip arthroplasty. The purpose of this study was to compare polyethylene wear in patients who had undergone bilateral total hip arthroplasty with implants that differed only with regard to the material used for the femoral head: a zirconia head was used on one side, and a cobalt-chromium head was inserted on the contralateral side. A prospective, randomized study was performed to evaluate the outcomes in fifty-two patients who had undergone sequential bilateral primary total hip replacement. A zirconia head was used in one hip, and a cobalt-chromium head was used in the other. There were forty-eight men and four women; the mean age at the time of surgery was 44.2 years. The mean duration of follow-up was 7.1 years. Clinical and radiographic evaluations were performed preoperatively and at six weeks; three, six, and twelve months; and yearly postoperatively. Linear wear of the polyethylene liner was measured radiographically. Two femoral components with a zirconia head had aseptic loosening and were revised. The explanted heads were evaluated with use of interferometry, environmental scanning electron microscopy, and x-ray diffraction studies. The mean polyethylene wear rate was 0.08 mm/yr in association with the zirconia heads and 0.17 mm/yr in association with the cobalt-chromium heads (p = 0.004). The mean amount of volumetric polyethylene wear was 350.8 mm3 in association with the zirconia heads and 744.7 mm3 in association with the cobalt-chromium heads (p = 0.004). With regard to surface roughness, the Ra values of the two explanted zirconia heads were 15.87 and 17.35 nm and the Rpm values were 153.86 and 156.18 nm. Two identical zirconia heads that had not been implanted had Ra values of 5.31 and 5.48 nm and Rpm values of 65.27 and 66.35 nm. Four unimplanted cobalt-chromium heads that were identical to the ones implanted in this study had Ra values ranging between 25 and 50 nm and Rpm values ranging between 262.6 and 525.2 nm. Little phase transformation was noted in the two revised zirconia heads. The mean amount and rate of polyethylene wear were significantly lower in the hips with a zirconia head than they were in the hips with a cobalt-chromium head, presumably because the zirconia heads had a smoother articulating surface.
    The Journal of Bone and Joint Surgery 09/2005; 87(8):1769-76. · 3.23 Impact Factor
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    ABSTRACT: BACKGROUND: Zirconia was introduced as an alternative to alumina for use in the femoral head. The yttria stabilized zirconia material was improved by adding alumina. We evaluated highly cross-linked polyethylene wear performance of zirconia in total hip arthroplasty. The hypothesis was that alumina stabilized zirconia could decrease highly cross-linked polyethylene wear. METHODS: Highly cross-linked polyethylene wear was measured with a computerized method (PolyWare) in 91 hips. The steady-state wear rates were measured based on the radiographs from the first year postoperatively to the final follow-up and were compared between hips with yttria stabilized zirconia and alumina stabilized zirconia. RESULTS: The steady-state wear rate of highly cross-linked polyethylene against zirconia was 0.02 mm/year at a mean follow-up of 7 years. No significant difference was observed between groups with yttria stabilized zirconia and alumina stabilized zirconia. CONCLUSIONS: Addition of alumina to the zirconia material failed to show further reduction of highly cross-linked polyethylene wear and our hypothesis was not verified.
    BMC Musculoskeletal Disorders 05/2013; 14(1):154. · 1.88 Impact Factor

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