Ceramics in orthopaedics

H pital Lariboisière and the Laboratoire de Recherches Orthopédiques, Paris, France.
The Bone & Joint Journal (Impact Factor: 3.31). 12/2000; 82(8):1095-9. DOI: 10.1302/0301-620X.82B8.11744
Source: PubMed
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Available from: Moussa Hamadouche, Apr 29, 2014
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    • "Currently there are two generations of ceramics available in the market. The third generation of ceramic, BIOLOX forte (CeramTec, Plochingen, Germany), is an alumina (aluminum oxide [Al 2 O 3 ]) nonmetallic material with a crystalline monophasic structure [7] [8]. Existing in a fully oxidized state provides great strength and hardness that makes ceramics a valuable bearing surface. "
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    ABSTRACT: Traditionally, metal-on-polyethylene has been the gold standard bearing in total hip arthroplasty. Ceramics were introduced as an alternative bearing because of their superior mechanical properties. Our institution has found ceramic-on-polyethylene has consistently shown lower in vivo wear rates compared to metal-on-polyethylene. The latest generation of ceramic-on-polyethylene, BIOLOX delta-on-highly cross-linked polyethylene, has shown an excellent linear wear rate (0.006 mm/y), which is much lower than previously found wear rates for cobalt-chrome-on-highly cross-linked polyethylene (0.011 mm/y). The minimal wear rate of BIOLOX delta-on-highly cross-linked polyethylene provides the potential to increase long-term survivorship and become the new gold standard bearing in THA.
    Seminars in Arthroplasty 01/2014; 24(4). DOI:10.1053/j.sart.2014.01.006
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    • "Zirconia ceramic has three phases of physical structure. The tetragonal phase has the greatest toughness and is used for the manufacture of prosthetic femoral heads, but it is also the most unstable phase with possible surface transformation back into the more stable monoclinic phase [5,6]. Alloying pure zirconia with stabilizing oxides such as MgO and Y2O3 allows the retention of the tetragonal structure at room temperature [7]. "
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    ABSTRACT: Background Zirconia was introduced as an alternative to alumina for use in the femoral head. The yttria stabilized zirconia material was improved by adding alumina. We evaluated highly cross-linked polyethylene wear performance of zirconia in total hip arthroplasty. The hypothesis was that alumina stabilized zirconia could decrease highly cross-linked polyethylene wear. Methods Highly cross-linked polyethylene wear was measured with a computerized method (PolyWare) in 91 hips. The steady-state wear rates were measured based on the radiographs from the first year postoperatively to the final follow-up and were compared between hips with yttria stabilized zirconia and alumina stabilized zirconia. Results The steady-state wear rate of highly cross-linked polyethylene against zirconia was 0.02 mm/year at a mean follow-up of 7 years. No significant difference was observed between groups with yttria stabilized zirconia and alumina stabilized zirconia. Conclusions Addition of alumina to the zirconia material failed to show further reduction of highly cross-linked polyethylene wear and our hypothesis was not verified.
    BMC Musculoskeletal Disorders 05/2013; 14(1):154. DOI:10.1186/1471-2474-14-154 · 1.72 Impact Factor
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    • "Comparative physical properties of alumina and zirconia ceramics of surgical grade [6] "
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    ABSTRACT: This research was to study the biocompatibility of in-house ceramic materials; consisted of different ratios of magnesium-doped alumina (MDA) and yttria-stabilized zirconia (YSZ). Materials 1-3 (M1-3) were 40, 50 and 60% MDA, respectively. Six male dogs were used for subcutaneous implants in the right hind limb for a 12-week period. Blood was collected from dogs weekly to evaluate health. Tissue surrounding material was then collected for histological evaluation and real-time PCR. Five transcripts, including TNF-α, IL-6, IL-13, IFN-g and MMP-9, were quantified using real-time PCR. The hardness of all materials was tested prior to and after implantation. The results found that all of the biopsy specimens showed neither foreign body reaction nor granulation tissue formation. Compared to the control, expression of MMP-9 in M1 was found to be significantly down-regulated (P < 0.05); expression of TNF-α, IL-13 and MMP-9 in M2 was found to be significantly different (P < 0.05); and in M3, IL-13 was found to be significantly up-regulated (P < 0.05). Hardness in M1 was significantly decreased (P < 0.05) after 12 weeks of implantation. In conclusion, M3, which consisted of 60% MDA, is a candidate material for use as a bone substitute in dogs.
    Chiang Mai Journal of Science 01/2013; 40(4):763-774. · 0.37 Impact Factor
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