Zinc and copper status in ewes supplemented with sulfate- and amino acid-complexed forms of zinc and copper.

Department of Animal and Range Sciences, Montana State University, Bozeman 59717-2900, USA.
Journal of Animal Science (Impact Factor: 2.11). 01/2001; 79(1):261-6.
Source: PubMed


Thirty 6-yr-old Targhee ewes were randomly allotted to one of five supplemental treatments to evaluate supplementation effects on liver and fecal Zn and Cu concentrations and serum alkaline phosphatase activity: 1) control, 2) Zn complex, 3) Zn and Cu (ZnCu) complex, 4) Zn sulfate, and 5) ZnCu sulfates. Supplements were administered daily in gelatin capsules for 56 d. Liver biopsies and serum samples were collected every 14 d starting on d 0. Supplemental Zn and Cu levels were formulated to provide 90 mg/kg Zn and 10 mg/kg Cu, respectively, on a daily dry matter intake basis. Form (complex vs sulfate) x type (Zn vs ZnCu) interactions were not detected (P > 0.35). Therefore, contrast statements were used to make the following treatment comparisons: 1) control vs supplement, 2) Zn vs ZnCu, and 3) complex vs sulfate. Ewe BW at the end of the study (P = 0.09) and ewe BW change from beginning to end of the study (P = 0.07) were greater for supplemented than control ewes. Body weight and BW change did not differ between sulfate and complex (P > 0.39) or Zn- and ZnCu- (P > 0.40) supplemented ewes. Liver Cu concentrations did not differ (P = 0.41) between control and supplemented ewes. Liver Cu concentrations were higher (P < 0.10) for ewes supplemented with ZnCu than Zn and complex than sulfate forms of supplement. Liver Zn concentration tended (P = 0.13) to be higher in ZnCu than Zn-supplemented ewes. Liver and fecal Zn concentration were higher (P < 0.06) in ewes fed complex than sulfate supplements. However, serum alkaline phosphatase activity tended (P = 0.12) to be greater in ewes fed sulfate than complex supplements. Supplementing mature ewes with complexed minerals resulted in higher concentrations of Zn and Cu in the liver. In addition, supplemental Cu tended to increase concentrations of Zn in the livers of ewes; however, high levels of supplemental Zn did not negatively impact liver Cu concentrations.

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Available from: Rodney W Kott, Jun 02, 2015
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    • "ganic minerals at the beginning ( p<0 . 0001 ) and end ( p = 0 . 02 ) of the growing phase . However , this difference was not present at the end of the finishing phase . In contrast to the present study , ewes supplemented with organic Zn ( Zn amino acid complex ) tended to have greater liver Cu concentrations than ewes supplemented with ZnSO 4 ( Hatfield et al . , 2001 ) . This effect was also reported in cows ( Ahola et al . , 2004 ) . Steers supplemented with organic Zn tended ( p<0 . 07 ) to have greater liver Mn concentrations than steers supplemented with inorganic Zn in the finishing phase . Spears ( 1996 ) proposed a theory that organic sources of minerals were more bioavailable than inorganic "
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