Rotheram-Borus MJ, Lee MB, Murphy DA, et al. Efficacy of a preventive intervention for youths living with HIV

Department of Psychiatry, University of California, Los Angeles, USA.
American Journal of Public Health (Impact Factor: 4.55). 04/2001; 91(3):400-5. DOI: 10.2105/AJPH.91.3.400
Source: PubMed


HIV transmission behaviors and health practices of HIV-infected youths were examined over a period of 15 months after they received a preventive intervention.
HIV-infected youths aged 13 to 24 years (n = 310; 27% African American, 37% Latino) were assigned by small cohort to (1) a 2-module ("Stay Healthy" and "Act Safe") intervention totaling 23 sessions or (2) a control condition. Among those in the intervention condition, 73% attended at least 1 session.
Subsequent to the "Stay Healthy" module, number of positive lifestyle changes and active coping styles increased more often among females who attended the intervention condition than among those in the control condition. Social support coping also increased significantly among males and females attending the intervention condition compared with those attending the control condition. Following the "Act Safe" module, youths who attended the intervention condition reported 82% fewer unprotected sexual acts, 45% fewer sexual partners, 50% fewer HIV-negative sexual partners, and 31% less substance use, on a weighted index, than those in the control condition.
Prevention programs can effectively reduce risk acts among HIV-infected youths. Alternative formats need to be identified for delivering interventions (e.g., telephone groups, individual sessions).

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Available from: Donna Futterman, Oct 02, 2015
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    • "In addition to potentially transmitting HIV to others, unprotected sex and shared drug injection among HIV-positive individuals may lead to STDs, other blood-borne infections, including hepatitis B and C virus, and HIV-1 reinfection—all of which can accelerate progression to AIDS (Blackard, Cohen, & Mayer, 2002; Filippini et al., 2001; O'Brien et al., 1999; Wiley et al., 2000). Studies have shown that following notification of their HIV–positive serostatus, most people living with HIV/AIDS make and maintain changes in their sexual and injection drug use practices (Crepaz & Marks, 2002; Kalichman et al., 2001; Rotheram-Borus et al., 2001). However, due to limited access to confidential HIV counseling and testing in Vietnam, few IDUs are aware of their HIV-status (Bergenstrom et al., 2007). "
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    ABSTRACT: The HIV epidemic in Vietnam is concentrated primarily among injecting drug users (IDUs). To prevent HIV-1 superinfection and to develop effective HIV prevention programs, data are needed to understand the characteristics of high-risk HIV-positive IDUs. In 2003 , we conducted a community-based cross-sectional study among predominately male, out-of-treatment IDUs, aged 18?45, in the Bac Ninh Province, Vietnam. Among 299 male participants, 42.8% were HIV-positive, and among those, 96.9% did not know their status prior to the study. Furthermore, 32% were HIV-positive and had high HIV behavioral risk (having unprotected sex or having shared injecting equipment in the past 6 months). Injecting for ?3 years, younger age, and pooling money to buy drugs were independently associated with being at high risk for transmitting HIV. IDUs who purchased more than one syringe at a time were less likely to have high HIV behavioral risk. Structural interventions that increase syringe accessibility may be effective in reducing HIV risk behavior among HIV-positive IDUs. Study limitations are noted in the article.
    Substance Use &amp Misuse 02/2011; 46(4):381-9. DOI:10.3109/10826084.2010.505147 · 1.23 Impact Factor
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    • "Antiretroviral therapy can lower viral load and reduce infectiousness, thereby reducing transmission and arguably lowering HIV incidence rates (Kalichman et al., 2010). Moreover, prior research indicates that when individuals become aware of their positive serostatus, they reduce risk behavior (Crepaz & Marks, 2002; Kalichman, Rompa & Cage, 2000; Rotheram-Borus et al., 2001). Since some people are unaware of their serostatus, The Strategy set a goal to increase people's awareness of their HIV status from 79% to 90% (The White House Office of National AIDS Policy, 2010). "
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    • "Risk reduction interventions designed to reduce HIV transmission risk behaviours in people who know they are HIV-positive have demonstrated risk reduction benefits in several studies conducted in the USA [9] [10] [11] [12] [13]. Within African contexts, the massive roll out of ARV treatment, presented an excellent opportunity for healthcare providers to link prevention with care for PLWHA. "
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    ABSTRACT: This paper presents the findings of an exploratory study to investigate the challenges faced by people living with HIV/AIDS (PLWHA) in communities in Cape Town, South Africa. The primary goal of the study was to gather data to inform the adaptation of a group risk reduction intervention to the South African context. Qualitative methods were used to examine the experiences of PLWHA. Eight focus group discussions (FGDs) were conducted with 83 HIV-positive participants and 14 key informants (KIs) involved in work with PLWHA were interviewed. Findings revealed that AIDS-related stigma was still pervasive in local communities. This was associated with the difficulty of disclosure of their status for fear of rejection. Also notable was the role of risky behaviours such as lack of condom use and that PLWHA considered their HIV/AIDS status as secondary to daily life stressors like poverty, unemployment, and gender-based violence. These findings have implications for the adaptation or development of behavioural risk reduction interventions for PLWHA.
    AIDS research and treatment 09/2010; 2010:420270. DOI:10.1155/2010/420270
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