Insomnia, fatigue, anxiety, depression, and quality of life of cancer patients undergoing chemotherapy.
ABSTRACT The purposes of this study were to examine: (a) the relationships between the symptoms of insomnia and fatigue and the psychological factors of anxiety and depression, and; (b) the relationships between these psychological and symptom variables and quality of life in cancer patients who were receiving chemotherapy. The Theory of Unpleasant Symptoms was the framework for the study. A descriptive correlational design was used in a secondary analysis of data obtained from a sample of 263 cancer patients who were undergoing chemotherapy. Insomnia, fatigue, depression, and anxiety were positively correlated with one another (r = .26 to r = .69, p < .001) and negatively correlated with quality of life (r = -.28 to r = -.63, p < .001). Women had more anxiety and fatigue and poorer quality of life than did men. Older age was associated with better quality of life and less insomnia, fatigue, anxiety, and depression. Multiple regression analysis revealed that the symptoms and psychological variables explained 47% of the variance in quality of life, with the largest proportion of the variance explained by depression. Fatigue and insomnia explained only 4% of the variance in quality of life in excess of that contributed by the psychological factors. Although overall depression levels were low in this sample, these findings suggest that insomnia and fatigue are related to depression and that depression is more closely associated with quality of life than are insomnia and fatigue.
SourceAvailable from: Renatha Rafihi-Ferreira[Show abstract] [Hide abstract]
ABSTRACT: Insomnia is a frequent complaint in patients with breast cancer and its consequences can impact the quality of life and course of the disease. The aim of this study was to review the literature on the relationship between insomnia and breast cancer, addressing the definition, prevalence, etiological factors and consequences of insomnia within the context of breast cancer, as well as treatments for insomnia in this population. A review of the literature searched the databases Scopus, Web of Science and Sciello using Uniterms: insomnia, sleep, breast cancer, treatment, cognitive-behavioral therapy. The studies reviewed showed that the etiology of insomnia involves predisposing, precipitation and perpetuation factors. This study highlights the importance of improved quality of sleep in cancer patients, and indicates the combination of pharmacotherapy and cognitive-behavioral treatment for sleep problems.Estudos de Psicologia (Campinas) 12/2012; 29(4):597-607. DOI:10.1590/S0103-166X2012000400014
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ABSTRACT: Evidence suggests a high prevalence of sleep-wake disturbances in patients with cancer, occurring at diagnosis, during treatment, and continuing to survivorship. Yet associations between sleep-wake disturbances and the impact on quality of life outcomes is less clear. The purpose of this narrative review of the literature is to evaluate sleep-wake disturbances in patients with cancer, to describe the influence of poor sleep on quality of life as an outcome, and to evaluate the evidence to recommend future interventions.Nature and Science of Sleep 07/2014; 6:85-100. DOI:10.2147/NSS.S34846This article is viewable in ResearchGate's enriched formatRG Format enables you to read in context with side-by-side figures, citations, and feedback from experts in your field.
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ABSTRACT: Although sleep is vital to all human functioning and poor sleep is a known problem in cancer, it is unclear whether the overall prevalence of the various types of sleep disorders in cancer is known. The purpose of this systematic literature review was to evaluate if the prevalence of sleep disorders could be ascertained from the current body of literature regarding sleep in cancer. This was a critical and systematic review of peer-reviewed, English-language, original articles published from 1980 through 15 October 2013, identified using electronic search engines, a set of key words, and prespecified inclusion and exclusion criteria. Information from 254 full-text, English-language articles was abstracted onto a paper checklist by one reviewer, with a second reviewer randomly verifying 50% (k = 99%). All abstracted data were entered into an electronic database, verified for accuracy, and analyzed using descriptive statistics and frequencies in SPSS (v.20) (North Castle, NY). Studies of sleep and cancer focus on specific types of symptoms of poor sleep, and there are no published prevalence studies that focus on underlying sleep disorders. Challenging the current paradigm of the way sleep is studied in cancer could produce better clinical screening tools for use in oncology clinics leading to better triaging of patients with sleep complaints to sleep specialists, and overall improvement in sleep quality.Cancer Medicine 11/2014; 4(2). DOI:10.1002/cam4.356